Exceptional dry spells, in this study referred to as very long dry spells (VLDS), are natural hazards to which the Mediterranean region is extremely vulnerable, with socio-economic and environmental impacts. In this study, they are characterized in terms of location, spatial extent, duration, temporal variability and associated atmospheric circulations. The main objective is to assess the performance of five HyMeX/Med-CORDEX regional climate simulations to detect and reproduce VLDS in comparison with the E-OBS observed daily gridded data. Models accurately reproduce the occurrence of precipitation around the Mediterranean Basin, and therefore the occurrence of VLDS, with at least 51% of the E-OBS VLDS reproduced by the regional simulations. They also accurately simulate the spatiotemporal characteristics. A second objective is to identify the synoptic atmospheric patterns associated with VLDS. A clustering analysis shows that all models accurately reproduce the main VLDS spatial patterns, associated with anticyclonic conditions above the affected regions. The simulated VLDS occurrence is strongly related to the amplitude of the sea level pressure and 500-hPa geopotential height anomalies as well as the location of the maximum anomalies. All VLDS events are associated with anticyclonic conditions except those occurring in the eastern Mediterranean, where they are generally not associated with a specific meteorological event but with the usual summer weather regime.