Marriage and mortality after acute coronary syndrome

Takagi, Hisato; Hari, Yosuke; Nakashima, Kouki; Kuno, Toshiki; Ando, Tomo

doi:10.1177/2047487319881832

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…Previous evidence has shown an association between married individuals and a lower incidence of CVD and coronary heart disease (CHD) and lower CHD and stroke mortality compared with unmarried individuals [28], which is in agreement with our results, where a majority of the participants with lower levels of MetSSS were married. Our results in which women showed higher levels of MetSSS is in agreement with previous observations in which women showed a higher risk of CV mortality attributed to the higher prevalence of MetS in elderly women [29] and the distribution of central adiposity, insulin resistance, and hormonal regulation [30].…”

Section: Sociodemographic Factorssupporting

confidence: 93%

“…Our results also agree previous findings in which total, red, and processed meat consumption is positively associated with MetS [27], which could potentially increase the risk of chronic diseases, including T2DM, CVD, and several types of cancer [47]. Conversely, our lowest severity MetSSS participants tended to have a higher intake of white meat, like previous findings that showed an inverse association between white meat intake and MetS [28].…”

Section: Dietary Characteristicssupporting

confidence: 92%

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Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study

Gallardo-Alfaro¹,

Bibiloni²,

Mascaró³

et al. 2020

Nutrients

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Healthy lifestyle factors, such as physical activity (PA) and Mediterranean diet (MD), decrease the likelihood of developing metabolic syndrome (MetS). The aim of this study was to report main lifestyle components and related factors according to the MetS severity. Cross-sectional analysis was done of baseline lifestyle factors from 5739 participants with overweight/obesity and MetS features (aged 55-75 years) included in the PREDIMED-PLUS primary cardiovascular prevention randomized trial. Participants were categorized in tertiles according to a validated MetS severity score (MetSSS). Anthropometrics, visceral adiposity index, dietary nutrient intake, biochemical marker levels, as well as a Dietary Inflammatory Index and depression symptoms (Beck Depression Inventory-II) were measured. Diet quality was assessed using a 17-item energy-restricted MD questionnaire. Duration and intensity of PA was self-reported using the Minnesota-REGICOR Short Physical Activity Questionnaire. Sedentary behaviours were measured using the Spanish version of the Nurses' Health Study questionnaire. The 30 s chair stand test was also assessed. Participants with highest MetSSS showed higher values of cardiovascular risk factors (except for total cholesterol and LDL cholesterol), depression risk, sedentary and TV viewing time, and lower moderate and vigorous Nutrients 2020, 12, 1013 3 of 20 leisure-time physical activity (LTPA). Highest MetSSS participants tended to a pro-inflammatory dietary pattern and tended to lower MD adherence. In addition, they showed lower carbohydrate and nut intake and higher intake of protein, saturated and trans fatty acids, cholesterol, iodine, sodium, red and processed meat products, other oils different from olive oil and spirit alcoholic drinks. The highest MetS severity score was associated with lower moderate and vigorous LTPA and higher sedentary time and depression risk, as they tended to a pro-inflammatory dietary pattern and lower MD adherence.

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Section: Sociodemographic Factorssupporting

confidence: 93%

Section: Dietary Characteristicssupporting

confidence: 92%

Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study

Gallardo-Alfaro¹,

Bibiloni²,

Mascaró³

et al. 2020

Nutrients

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“… 21 , 22 Moreover, spouses of married patients may supervise medication or promote medical advice seeking, which may also account for the protective effect. 23 , 24 Wu et al reported worse cardiac event‐free survival in unmarried patients with heart failure than in married counterparts, and the worse adherence to medications mediates this disparity. 25 …”

Section: Discussionmentioning

confidence: 99%

Impact of Marital Status on Management and Outcomes of Patients With Acute Myocardial Infarction: Insights From the China Acute Myocardial Infarction Registry

Wei

Yang

Hua

et al. 2022

JAHA

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Background Acute myocardial infarction (AMI) is one of the leading causes of mortality worldwide, whereas social support is a known predictor of the prognosis after AMI. As a common factor influencing social support, the impact of marital status on care quality, in‐hospital mortality, and long‐term prognosis of patients with AMI remains largely unknown. Methods and Results The present study analyzed data from the CAMI (China Acute Myocardial Infarction) registry involving 19 912 patients with AMI admitted at 108 hospitals in China between January 2013 and September 2014 and aimed to evaluate marital status–based differences in acute management, medical therapies, and short‐term and long‐term outcomes. The primary end point was 2‐year all‐cause death. The secondary end points included in‐hospital death and 2‐year major adverse cardiac and cerebrovascular events (a composite of all‐cause death, myocardial infarction, or stroke). After multivariable adjustment, 1210 (6.1%) unmarried patients received less reperfusion treatment in patients with both ST‐segment–elevation myocardial infarction and non–ST‐segment–elevation myocardial infarction (adjusted odds ratio [OR], 0.520 [95% CI, 0.437–0.618]; P <0.0001; adjusted OR, 0.489 [95% CI, 0.364–0.656]; P <0.0001). Being unmarried was not associated with poorer in‐hospital outcome but with long‐term all‐cause mortality and major adverse cardiac and cerebrovascular events in both ST‐segment–elevation myocardial infarction (adjusted hazard ratio [HR], 1.225 [95% CI, 1.031–1.456]; P =0.0209; adjusted HR, 1.277 [95% CI, 1.089–1.498]; P =0.0027) and non–ST‐segment–elevation myocardial infarction (adjusted HR, 1.302 [95% CI, 1.036–1.638]; P =0.0239; adjusted HR, 1.368 [95% CI, 1.105–1.694]; P =0.0040) populations. Conclusions The present study suggests that being unmarried is independently related to less reperfusion received, but could not explain the higher in‐hospital mortality rate after covariate adjustment. Being unmarried is associated with a substantially increased risk of adverse events over at least the first 24 months after AMI. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT01874691.

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“…Acute coronary syndrome (ACS) is one of the leading causes of acute chest pain, requiring emergency care and eventual hospitalization [1][2][3]. An accurate assessment of the clinical setting is needed to ensure that the patient is correctly managed.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Wellens’ Syndrome in the Current PCI Era: A Single-Center Retrospective Study

Zhou

Gong

Chen

et al. 2023

Emergency Medicine International

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Objectives. The goal of this retrospective study was to reveal the prevalence, angiographic characteristics, clinical presentation, and long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI) patients with Wellens’ syndrome. Background. Procedural results for percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) have improved in recent years. However, there is still a paucity of available clinical trial data for Wellens’ syndrome even though it is a well-known high-risk ACS. Methods. Among a total of 3528 patients with ACS who underwent angioplasty from 2017 to 2019 at the Cardiovascular Center of Beijing Friendship Hospital, 476 NSTEMI patients with culprit left anterior descending (LAD) vessels were enrolled in this study. According to electrocardiographic criteria of Wellens’ syndrome, the patients were divided into a Wellens group (n = 138) and a non-Wellens group (n = 338). The primary endpoint was cardiac death; the secondary endpoints were main adverse cardiovascular and cerebrovascular events (MACCEs), a composite of all-cause death, cardiac death, heart failure, target lesion revascularization, recurrent myocardial infarction, and stroke. All of the medical and follow-up data were obtained from our institutional database. Results. The incidence of Wellens’ syndrome in all ACS patients was 5.7% (200 of 3528). Among the 200 patients with Wellens’ syndrome, 138 had NSTEMI, for a proportion of 69%. There was a significant decrease in the percentage of preexisting coronary heart disease (CHD), prior myocardial infarction, and previous PCI ( P < 0.05 ) in the Wellens group compared with the non-Wellens group. On coronary angiography, single-vessel lesions were more common in the Wellens group (11.6% vs. 5.3%, P = 0.016 ), and almost all (97.1%) of these patients received drug-eluting stents. Notably, the Wellens group had a higher proportion of early PCI than the non-Wellens group (71% vs. 61.2%, P = 0.044 ). At 24 months, there was no statistically significant difference in cardiac death ( P = 0.111 ) between the two groups, but the MACCEs were comparable (Wellens: 5.1% vs. non-Wellens: 13.3%, P = 0.009 ). Age ≥65 years was the largest independent risk factor for adverse prognosis. Conclusions. With early recognition and aggressive intervention, Wellens’ syndrome is no longer a risk factor for adverse prognosis in patients with NSTEMI in the current PCI era.

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Marriage and mortality after acute coronary syndrome

Cited by 4 publications

References 10 publications

Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study

Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study

Impact of Marital Status on Management and Outcomes of Patients With Acute Myocardial Infarction: Insights From the China Acute Myocardial Infarction Registry

Characteristics of Wellens’ Syndrome in the Current PCI Era: A Single-Center Retrospective Study

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