2023
DOI: 10.1016/j.modpat.2022.100088
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MarrowQuant 2.0: A Digital Pathology Workflow Assisting Bone Marrow Evaluation in Experimental and Clinical Hematology

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Cited by 5 publications
(4 citation statements)
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“…However, their tests were limited to single observer, whereas our model's performance was compared with that of five expert hematopathologists. Sarkis et al [32] also compared the performance of a model for BMB cellularity assessment with that of four pathologists, obtaining a high level of concordance with all four. However, the model developed by Sarkis et al required semi-automated interaction, necessitating user involvement for performing a white color balance, making three annotations (for the tissue to be evaluated), and selecting the background and artifacts before analyzing the entire BMB.…”
Section: Discussionmentioning
confidence: 99%
“…However, their tests were limited to single observer, whereas our model's performance was compared with that of five expert hematopathologists. Sarkis et al [32] also compared the performance of a model for BMB cellularity assessment with that of four pathologists, obtaining a high level of concordance with all four. However, the model developed by Sarkis et al required semi-automated interaction, necessitating user involvement for performing a white color balance, making three annotations (for the tissue to be evaluated), and selecting the background and artifacts before analyzing the entire BMB.…”
Section: Discussionmentioning
confidence: 99%
“…Hematoxylin (Sigma-Aldrich) and eosin (Sigma-Aldrich) stained slides (section thickness 4 nm) were scanned using the Nanozoomer SQ (Hamamatsu Photonics) 40x objective. To evaluate automatically and reproducibly the tissue slides, the open-source software QuPath [27] implemented with the MarrowQuant 2.0 script was used [28].…”
Section: Histological Preprocessing Slides Acquisition and Analysismentioning
confidence: 99%
“…FlowJo Software (BD) was used to analyze flow cytometry data. QuPath´s script MarrowQuant 2.0 was used to automatically quantify histology-stained tissue slides (code and tutorials available at https:// github.com/Naveiras-Lab/MarrowQuant2.0) [28]. Compression testing data was analyzed using a custom-made MATLAB script.…”
Section: Data Analysis Statistics and Presentationmentioning
confidence: 99%
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