Marshall syndrome in a young child, a reality

Trandafir, Laura Mihaela; Chiriac, Madalina Ionela; Diaconescu, Smaranda; Ioniuc, Ileana; Miron, Ingrith; Rusu, Daniel

doi:10.1097/md.0000000000005065

Cited by 9 publications

(8 citation statements)

References 13 publications

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“…Only in two cases dilution of 1:200,000 was used due to cardiac comorbidities of the patients [18,19]. As far as patient satisfaction is concerned, it was maximum in terms of both intraoperative comfort and length of hospital stay that was reduced to a few hours [19][20][21][22].…”

Section: Resultsmentioning

confidence: 99%

Study on Epinephrine Used in Local Anesthesia Controversy and certainty

Perţea¹,

Poroch²,

Grosu³

et al. 2018

Rev. Chim.

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Epinephrine (adrenaline) - C9H13NO3 - was synthesized for the first time by Fredrich Stelz in 1904 from phenylalanine. After a hydrolysis and decarboxylation process, active dopamine is obtained. Following the pathway of other hydroxylation followed by N-methylation, epinephrine synthesis is achieved. Epinephrine has initially been administrated together with procaine in local anesthesia in hand surgery. Epinephrine has been considered to be one of causes of ischemia and necrosis in hand and especially fingers surgery. Over time, studies have shown the efficacy and safety of using lidocaine-associated epinephrine in local hand surgery anesthesia. Numerous advantages regarding the use of lidocaine 1% with epinephrine, solution at a concentration of 1:100,000 have been reported, starting with increasing the duration of anesthesia, avoiding the use of tourniquet, leading to increased patient comfort and to the advantage of a much lower cost in terms of surgery as a whole. Our study group consisted of fifty patients with hand and fingers different patologies. In all cases surgery was performed under local anesthesia using lidocaine 1% with epinephrine, solution at a concentration of 1:100,000. The decrease of doses mentioned in the literature was attempted and in some cases the decrease was up to 30%. There have not been reported any ischemic or necrosis complication in the immediate postoperative period.

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Section: Resultsmentioning

confidence: 99%

Study on Epinephrine Used in Local Anesthesia Controversy and certainty

Perţea¹,

Poroch²,

Grosu³

et al. 2018

Rev. Chim.

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“…Numerous studies demonstrating the efficacy and versatility of that matrix-forming agent are provided in the literature [8]. Similar studies were carried out in the literature [9][10][11][12][13][14][15][16][17][18][19][20][21].…”

mentioning

confidence: 99%

Study on the Formulation and Pharmacotechnical Characterization of Hydrophilic Matrix Tables with Amiodarone Chlorhydrate

Crețeanu¹,

Ştefanache²,

Vieriu³

et al. 2019

Rev. Chim.

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The study is based on new oral matrix tablets based on Kollidon®SR and chitosan, formulated in order to optimize the low oral bioavailability of amiodarone, a class III antiarrhythmic drug. Pharmacotechnical characterization included the analysis of flowability and compressibility properties (flow time, friction coefficient, angle of repose, Hausner ratio, Carr Index), and of pharmaco-chemical characteristics (mass and dose uniformity, thickness, diameter, mechanical strength, friability, degree of softening, in vitro release profile) of the tablets obtained using direct compression method. The results obtained have shown that both Kollidon®SR and chitosan may be used as matrix forming agents when combined with amiodarone. In vitro dissolution tests revealed that the nine formulations studied provided a prolonged release of amiodarone when compared to an industrial pharmaceutical product formulated as conventional release tablets.

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“…Intercalation of this antibiotic into LDHs structure ( fig. 1) improves antimicrobial treatment by increasing intracellular delivery thus reducing toxic side effects [17][18][19][20][21][22][23][24][25][26][27][28].…”

mentioning

confidence: 99%

Ceftriaxone Intercalated Nanostructures Used to Improve Medical Treatment

Duceac¹,

Luca²,

Mitrea³

et al. 2018

Mat.Plast.

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The development of antibiotic resistance in bacteria possesses a huge threat to public health by nullifying the effect of even the most efficient antibiotics. From years, LDHs type nanomaterials have been used as drug carriers for a wide variety of pharmaceutically active molecules due to their delivery properties, making these inorganic-organic nanohybrids very efficient antimicrobial agents. The major purpose of this work was to synthesize and characterize ceftriaxone intercalated layered nanostructures for further use to treat some infections, mostly of them child infections. The novel nanohybrid materials were prepared by ion exchange route and coprecipitation method. Structural and morphological characterization was performed by FTIR, EDX and SEM techniques. The results revealed a high incorporation of the drug in the interlayer space of promising nanostructures.

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Marshall syndrome in a young child, a reality

Cited by 9 publications

References 13 publications

Study on Epinephrine Used in Local Anesthesia Controversy and certainty

Study on Epinephrine Used in Local Anesthesia Controversy and certainty

Study on the Formulation and Pharmacotechnical Characterization of Hydrophilic Matrix Tables with Amiodarone Chlorhydrate

Ceftriaxone Intercalated Nanostructures Used to Improve Medical Treatment

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