Masked hypertension: a systematic review

Bobrie, Guillaume; Clerson, Pierre; Ménard, J; Postel-Vinay, Nicolas; Châtellier, Gilles; Plouin, Pierre‐François

doi:10.1097/hjh.0b013e3282fbcedf

Cited by 246 publications

(148 citation statements)

References 57 publications

(137 reference statements)

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“…Ambulatory BP level had already many years ago been shown to be better predictor for cardiovascular complications as compared to clinic BP readings [24,25]. This was confirmed by prospective studies dealt with estimation of outcomes in patients with different BP phenotypesrisk of myocardial infarction, stroke, lethal outcomes and other cardiovascular complications was significantly higher in masked uncontrolled hypertension as compared to normotension and well controlled hypertension and was similar to cardiovascular risk in sustained hypertension [7,[26][27][28][29]. For instance, in accordance to Satoh M. et al data [29] (with mean follow-up of 17.1 years) the risk of stroke in masked un-АГТ -38,8% зимой и 27,8% летом.…”

Section: Discussionsupporting

confidence: 57%

“…Уже мно-го лет назад был доказан факт, что амбулаторное АД -луч-ший предиктор сердечно-сосудистых осложнений по сравнению с показателями клинических измерений [24,25]. Это подтверждают и проспективные исследования, по-священные оценке исходов при разных фенотипах АД, -риск инфаркта миокарда, мозгового инсульта, летальных исходов и других сердечно-сосудистых осложнений при скрытой АГ значимо выше, чем при нормотонии и эф-фективной АГТ, а также сопоставим с риском при устойчивой АГ [7,[26][27][28][29]. Например, в исследовании Satoh M. и соавт.…”

Section: Discussionunclassified

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Blood Pressure Phenotypes in Treated Hypertensive Patients in Summer and Winter: Focus on Masked Uncontrolled Hypertension. Part 1: Blood Pressure Phenotypes Prevalence

Смирнова

Горбунов

Boytsov

et al. 2017

Racionalʹnaâ farmakoterapiâ v kardiologii

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Background. The seasonal variability of blood pressure (BP) and cardiovascular morbidity and mortality motivates researchers to search for the new approaches of the antihypertensive treatment (AHT) efficacy assessment, including the analysis of interrelation between clinic and ambulatory BP, i.e. BP phenotypes. Aim. To evaluate the prevalence of BP phenotypes in treated hypertensive outpatients both in winter and summer. Material and methods. Hypertensive patients under regular AHT with available data of clinic BP and 24-hour BP monitoring both in winter and summer seasons (n=477) were selected from a outpatient database with clinic BP <160/100 mm Hg (n=1762). The BP threshold values from current guidelines were used for the BP phenotypes definition. The "controlled hypertension" phenotype was detected when clinic and ambulatory BP levels were less than threshold values, the "uncontrolled hypertension" -when both levels exceeded the thresholds, the "white coat hypertension (WCH) in treated patients" -when clinic BP was only increased, the "masked uncontrolled hypertension" phenotype was ascertained if ambulatory BP was only elevated. Results. The study included 232 patients examined in Ivanovo (a relatively cold region; mean age 53.5±9.3 years; 28% men; clinic BP 121.7±7.9 mm Hg; mean duration of hypertension 4.6±6.3 years) and 245 patients from Saratov (a relatively hot region; mean age 58.3±10.6 years; 56.3% men; clinic BP 127.5±14.9 mmHg; mean duration of hypertension 9.2±9.2 years; р<0.0001). In the Ivanovo cohort, ratio of BP phenotypes in summer and winter did not differ; the "masked uncontrolled hypertension" phenotype prevailed (62.1% and 63.8% in winter and summer, respectively); AHT was effective in 27.6% and 29.7% of the patients in winter and summer, respectively. The prevalence of other phenotypes was low: uncontrolled hypertension -9.5% in winter and 6.0% in summer; WCH in treated patients -less than 1% in both seasons. The prevalence of BP phenotypes in the patients examined in Saratov differed in winter and summer (χ 2 =18.127, р<0.0001); the "masked uncontrolled hypertension" phenotype rate was higher in summer than in winter (50.2% and 32.2%, respectively); the rates of other phenotypes were higher in winter: uncontrolled hypertension -38.8% and 27.8%, controlled hypertension -25.3% and 20.8%, WCH -3.7% and 1.2% in winter and summer, respectively. Conclusion. We have found no seasonal changes in BP phenotypes prevalence in relatively younger hypertensive patients in a relatively cold region. The "masked uncontrolled hypertension" phenotype was predominant (>60%) in this region. In contrast, the cohort of relatively older patients with longer hypertension history examined in a relatively warmer region revealed significantly higher rate of masked uncontrolled hypertension in summer (50.2%) while prevalence of all other phenotypes -in winter.

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Section: Discussionsupporting

confidence: 57%

Section: Discussionunclassified

Blood Pressure Phenotypes in Treated Hypertensive Patients in Summer and Winter: Focus on Masked Uncontrolled Hypertension. Part 1: Blood Pressure Phenotypes Prevalence

Смирнова

Горбунов

Boytsov

et al. 2017

Racionalʹnaâ farmakoterapiâ v kardiologii

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“…In a systematic review of MH published recently, Bobrie et al [20] concluded that compared with subjects with normal BP or WCH, patients with MH "clearly have a higher BMI, and may even be obese". This conclusion is based in part on a report concerning 3400 treated hypertensive patients in Japan, in whom BMI ≥ 25 was an independent predictor of MH according to home BP monitoring (adjusted OR 1.38), whereas low BMI was predictive of WCH (adjusted OR 0.70) [21].…”

Section: White-coat and Masked Hypertensionmentioning

confidence: 97%

Ambulatory blood pressure monitoring in childhood and adult obesity

Ben‐Dov¹,

Bursztyn

2009

Current Science Inc

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Body mass and body fat are known modulators of blood pressure (BP) measured by clinic sphygmomanometry. However, the ambulatory BP-monitoring characteristics unique to obesity have not been widely studied. We reviewed the literature on ambulatory BP monitoring for links between measures of body adiposity in lean and overweight children and adults and various BP measures obtained by ambulatory monitoring. Collectively, the findings suggest significant associations of adiposity with ambulatory BP and heart rate, sleep-related BP dipping, and the white-coat phenomenon.

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“…They also provide better precision by capturing the BP fluctuations related to daily life and make it possible to capture "masked" hypertension, defined as elevated daytime ambulatory BP (≥135/85 mmHg) in the face of normal office BP (<140/90 mm Hg). The prevalence of masked hypertension has been estimated to be between 8-30% in the general population (201)(202)(203)(204). Several population-based studies and prospective clinical trials have provided clear evidence of the superiority of ambulatory over office BP measures in predicting cardiovascular risks (152,(205)(206)(207)(208).…”

Section: Methodological Characteristicsmentioning

confidence: 99%

Adverse effects of psychosocial work factors on blood pressure: systematic review of studies on demand–control–support and effort–reward imbalance models

Gilbert-Ouimet¹,

Trudel²,

Brisson³

et al. 2013

Scand J Work Environ Health

182

136

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This is the first systematic review and critical synthesis on the adverse effects of psychosocial work factors of the demand-control-support and effort-reward imbalance models on blood pressure. A more consistent effect has been observed among men than women and among studies of higher methodological quality. Evidence-based guidelines for cardiovascular diseases prevention may benefit from these findings.Affiliation: Population health research unit, St-Sacrement hospital,

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Masked hypertension: a systematic review

Cited by 246 publications

References 57 publications

Blood Pressure Phenotypes in Treated Hypertensive Patients in Summer and Winter: Focus on Masked Uncontrolled Hypertension. Part 1: Blood Pressure Phenotypes Prevalence

Blood Pressure Phenotypes in Treated Hypertensive Patients in Summer and Winter: Focus on Masked Uncontrolled Hypertension. Part 1: Blood Pressure Phenotypes Prevalence

Ambulatory blood pressure monitoring in childhood and adult obesity

Adverse effects of psychosocial work factors on blood pressure: systematic review of studies on demand–control–support and effort–reward imbalance models

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