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InThe exact mechanism that causes taste suppression in a perceptually heterogeneous mixture, and the locus of that mechanism, are as yet unknown. The present study was designed to explore the idea that mixture suppression is a perceptual phenomenon and not the result of physical, chemical, or receptor-substance interactions. An investigation was carried out as to whether perceptually similar taste stimuli give rise to the same sensory interactions when mixed with a substance of a different taste quality. In the first study, five different sweeteners (sucrose, fructose, aspartame, saccharin, and sorbitol) were matched in perceived sweetness intensity, in order to obtain five perceptually similar stimuli. Every equisweet sweetener concentration was mixed with each of four citric acid concentrations. In a second study, the sourness-suppressing effects of two sweeteners, sucrose and aspartame, were compared at four different concentration levels. Sourness scale values of unmixed citric acid, the unmixed sweeteners, and the citric acid/sweetener mixtures were assessed with a functional measurement approach in combination with a twostimulus procedure. The equisweet sweeteners were equally effective in suppressing the perceived sourness intensity of citric acid over the concentration range used. The side tastes of the sweeteners, if present, did not have a substantial effect on the degree of sourness suppression.When two or more substances of qualitatively different tastes are mixed, the overall perceived taste intensity of the mixture is, in most cases, less than the sum of the intensities of the unmixed components (see, e.g., Bartoshuk, 1975). This phenomenon, called mixture suppression, is the result of a decrease of the specific taste intensities (sweetness, sourness, saltiness, bitterness) contributing to the overall intensity of the solution (De Graaf & Frijters, 1989; Schifferstein & Frijters, 1990). The suppression of one taste quality by the other in a binary mixture is usually mutual, but not necessarily symmetrical. For example, Schifferstein and Frijters (1990) found that in a mixture of l.OOM sucrose and O.OlOM citric acid, the sweetness intensity of sucrose was suppressed by 11 units, while the sourness intensity of citric acid was suppressed by 52 units. The total taste intensities of the unmixed stimuli were comparable in strength, being 73 and 79 units, respectively.The exact mechanism that causes mixture suppression and the locus of that mechanism are as yet undetermined. Kroeze (1978) has shown that two phenomena that canThe authors gratefully acknowledge the funding provided by the Netherlands Organization for Scientific Research (NWO) for this project. The research was conducted while H. N. J. Schifferstein was supported by a NWO PSYCHON-grant No. 560-262-032, which had been awarded to J. E. R. Frijters. The authors also wish to thank MaIjon Theunissen, Hilda Srnit, and Liesbeth Hijwegen-Weemering for their assistance in collecting the data. Correspondence should be addressed to Hendrik N. J. ...