Masquerade syndrome: An eye problem as a manifestation of a more sinister disease

Reyes, M.C. Muñoz; Requena, J.M. Romero; Alcántara, Y. G. Piña; Álvarez-Arenas, J. Bueno; Cansado, Alberto

doi:10.1016/j.oftale.2018.11.002

Cited by 1 publication

(1 citation statement)

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“…Masquerade syndromes pose a significant challenge in the field of intraocular inflammations, as they can mimic uveitis and mislead clinicians, resulting in severe consequences for the patient's vision, general health, and even their life [ 55 ]. Rothova et al [ 56 ] reported the results of a study involving 1906 patients with intraocular inflammation.…”

Section: Discussionmentioning

confidence: 99%

The large Hellenic Study of Uveitis: epidemiology, etiologic factors and classification

et al. 2023

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Purpose To analyse the demography, etiology, and classification of uveitis at a tertiary academic referral center. Methods An observational study was conducted on the archives of uveitic patients at the Ocular Inflammation Service of the Department of Ophthalmology at the University Hospital of Ioannina (Greece) from 1991 to 2020. This study aimed to investigate the epidemiological profile of patients, including their demographics and the main etiologic factors of uveitis. Results Out of 6191 cases with uveitis, 1925 were infectious, 4125 were non-infectious, and an overall of 141 masquerade syndromes were recorded. Among these cases, 5950 patients were adults, with a slight female predominance, while 241 were children (< 18 years old). Interestingly, 24.2% of cases (1500 patients) were associated with 4 specific microorganisms. Herpetic uveitis (HSV-1 and VZV/HZV) was the most common cause of infectious uveitis (14.87%), followed by toxoplasmosis (6.6%) and tuberculosis (2.74%). In 49.2% of non-infectious uveitis cases, no systematic correlation was found. The most frequent causes of non-infectious uveitis included sarcoidosis, white dot syndromes, ankylosing spondylitis, lens-induced uveitis, Adamantiades-Behçet disease, and idiopathic juvenile arthritis. Infectious uveitis was more common in the rural population, whereas non-infectious uveitis was more frequently recorded in the urban population Conclusions Although our study was conducted on a predominantly white Caucasian population, it also reflects the effect of increasing immigration, improvements of diagnostic techniques, changes in referral patterns, and various actual changes in disease incidence.

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Section: Discussionmentioning

confidence: 99%