Nuclear mass continues to be of great importance for various aspects of nuclear physics, for instance, it is the basic building blocks of nuclear structure and nuclear astrophysics. In the study of nuclear structure, the mass of nucleus is an important parameter to validate the model theories and provide a limitation on parameters of theories. In nuclear astrophysics, masses of many nuclei far from line of stability play a vital role in the calculation of stellar nucleosynthesis. Since there is difficulties in measuring the key reaction of nuclear synthesis directly, the precise nuclei mass data can help us judge the importance of each possible nuclear synthesis path. Fe is indicated as a waiting point in stable nuclear burning on an accreting neutron star [5]. Its proton capture rate, which has a direct correlation with its mass, is one of the most important nuclear physics input parameters for the calculations of steady state burning on an accreting neutron star. Therefore, the mass of Fe 52 is an important input parameter in both nuclear structure and nuclear astrophysics.Mass measurements are pursued worldwide. There are a variety of ways that can determine the nuclear mass. The methods of measurement can be classified into two groups, direct and indirect method. The indirect measurement is an important way to determine the masses of nuclei, especially for the nuclei where the direct measurement is very difficult. There are two main indirect methods, Article available at