Mass Propagation of Plant Cells – An Emerging Technology Platform for Sustainable Production of Biopharmaceuticals

In Vitro Cell Culture of Rhus coriaria L.: A Standardized Phytocomplex Rich of Gallic Acid Derivatives with Antioxidant and Skin Repair Activity

“…Plant cell culture technology is a technique for the growing of plant cells under strictly controlled environmental conditions [1]. The derived extracts can be easily standardized in their primary and secondary metabolites and are compliant with the safety requirements of being contamination-free and phytochemically uniform [2].…”

A Phytocomplex Obtained from Salvia officinalis by Cell Culture Technology Effectively Controls the Grapevine Downy Mildew Pathogen Plasmopara viticola

“…Undifferentiated plant cells are considered totipotent and have the potential to express the whole genetic machinery coded in the nucleus. Thus, they can produce the full spectrum of characteristic secondary metabolites found in mother plants [ 10 ]. Plant cells are amenable to good manufacturing practice (GMP) procedures and can be easily propagated using large volume bioreactors regardless of climate, soil or field management practices [ 10 , 11 ].…”

“…Thus, they can produce the full spectrum of characteristic secondary metabolites found in mother plants [ 10 ]. Plant cells are amenable to good manufacturing practice (GMP) procedures and can be easily propagated using large volume bioreactors regardless of climate, soil or field management practices [ 10 , 11 ]. Moreover, in vitro cultured plant cells typically grow fast and can accumulate large amounts of uniform biomass in a short time [ 12 , 13 ].…”

In Vitro Cultured Melissa officinalis Cells as Effective Ingredient to Protect Skin against Oxidative Stress, Blue Light, and Infrared Irradiations Damages

“…Plant cell culture technology is a technique for growing plant cells under strictly controlled environmental conditions [5] that makes it possible to solve the problems tied to the variability of plant extracts, since it provides preparations with a content of active substances that can be reproduced in a standardized manner. The derived extracts can be easily standardized in their primary and secondary metabolites and are compliant with the safety requirements of being contamination-free and phytochemically uniform [6].…”