Mass spectrometry and stereochemistry of heterocyclic compounds (review)

Stereochemical effects in mass spectrometry

“…In the study of stereoisomeric methyl-substituted truns-perhydroquinolines (8,5657) it was noted that the abundance of the (M -CH3)+ ion was greater for 2a, with an axial 2-CH3 group, than for the epimeric 2b. This effect is even more pronounced in the substituted 4-hydroxydecahydroquinolines 3.…”