Mass spectrometry in environmental organic analysis

Levsen, K.

doi:10.1002/oms.1210230519

Cited by 36 publications

(8 citation statements)

References 135 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ultraviolet (UV)*-' electrochemical' 3-'4 or mass spectrometric detection.' 5-- 23 In the work described here the utility of ammonium formate as a buffer for TSP LC-MS will be domonstrated for the three different groups of herbicides mentioned before. Positive and negative ion modes (PI and NI, respectively) in TSP LC-MS will be employed for measuring adduct-ion formation.…”

Section: Introductionmentioning

confidence: 99%

Effect of ammonium formate as ionizing additive in thermospray liquid chromatography‐mass spectrometry for the determination of triazine, phenylurea and chlorinated phenoxyacetic acid herbicides

Barceló

1989

Org. Mass Spectrom.

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Effect of ammonium formate as ionizing additive in thermospray liquid chromatography‐mass spectrometry for the determination of triazine, phenylurea and chlorinated phenoxyacetic acid herbicides

Barceló

1989

Org. Mass Spectrom.

View full text Add to dashboard Cite

“…MS-MS spectra were obtained by collision-induced dissociation (CID). 26,27 Non-resonant excitation was selected for the compounds. The isolated precursor ions were selected from the full scan spectra of the compounds by taking into consideration its m/z and relative abundance (both as high as possible) in order to improve sensitivity and selectivity.…”

Section: Instrumental Variablesmentioning

confidence: 99%

Monitoring of 6-chloronicotinic acid in human urine by gas chromatography-tandem mass spectrometry as indicator of exposure to the pesticide imidacloprid

Uroz

Arrebola

González

et al. 2001

Analyst

View full text Add to dashboard Cite

A new analytical method for determining 6-chloronicotinic acid (6-ClNA) in human urine is proposed. 6-ClNA is the main metabolite in warm-blooded animals after exposure to the insecticide imidachloprid. 6-ClNA was extracted from human urine using solid phase extraction (SPE) with laboratory-made cartridges of Amberlite XAD-4. A clean-up step and a derivatization process were carried out prior to gas chromatography-tandem mass spectrometric (GC-MS-MS) determination. A study on the influence of pH in the extraction process revealed that it affects the analyte extraction efficiency. A working pH zone was defined between 0.8 and 2.8. Calibration curves were studied in the concentration range of 0.5-100 ng mL(-1) and showed good linearity. Limits of detection and determination of the method were 16 and 56 pg mL(-1) respectively. The mean recovery at 10 and 100 ng mL(-1) was between 97.2 and 102.1% and the repeatability was lower than 5.4% in all cases. The analysis of urine samples of five agricultural workers from Almería (Spain) did not detect the metabolite.

show abstract

“…An excellent book (11) and review articles (1,12) have been recently published reporting LC-MS applications in environmental pesticide analysis. Among the different LC-MS approaches, the thermospray (TSP) interfacing system is probably the most widely used and typically involves the use of reversed-phase columns and volatile buffers with or without a filament.…”

Section: The On-line Combination Of Liquid Chromâtography-mass Spectrmentioning

confidence: 99%

Use of Solvent Adduct Ions To Confirm Structure of Selected Herbicides with Thermospray Liquid Chromatography/Mass Spectrometry

Barceló

1990

ACS Symposium Series

View full text Add to dashboard Cite

Conventional positive-ion and negative-ion modes (PI and NI ,respectively), the use of ammonium acetate and ammonium formate and the addition of 2% chloroacetonitrile in the liquid chromatographic eluent using filament-on thermospray LC-MS have been applied for the determination of selected herbicides. By using acetonitrile-water and 0.05 M ammonium acetate mixtures, the chlorotriazine herbicides showed [M + (CH 3 CN)H] + and [M -H] -ions as base peaks in PI and NI modes, respectively. When ammonium formate and ammonium acetate were added to methanol-water eluent, the phenylurea herbicides exhibited in PI mode a relevant peak between 50-70% relative intensity corresponding to [M + (CH 3 OH)NH 4 ] + and [M + (CH 3 COOH)NH 4 ]+, respectively, whereas the base peak was [M + NH 4 ] + in both cases. The formation of [M + HCOOHNH 4 ] + was incidently observed in PI when ammonium formate was used. With this ionizing additive and NI the chlorinated phenoxyacid herbicides exhibited [M + HCOO] -as base peak, thus allowing a complementary structural information to [M + CH 3 COO] -, a typical ion obtained whenammonium acetate was added as ionizing additive. The addition of 2% chloroacetonitrile to acetonitrile-water eluent showed in NI mode a [M + Cl] -ion as base peak instead of [M + CH 3 COO] -or [M + HCCO] -ions in combination with other main ions which were assigned to [M -H] -and [M + H] -. Applications are reported for the determination of phenylurea and chlorinated phenoxyacid herbicides in spiked water samples by using PI and NI modes, respectively.

show abstract

Mass spectrometry in environmental organic analysis

Abstract: The use of mass spectrometry in environmental organic analysis is reviewed, with special emphasis on modern mass spectrometric methods.

Cited by 36 publications

References 135 publications

Effect of ammonium formate as ionizing additive in thermospray liquid chromatography‐mass spectrometry for the determination of triazine, phenylurea and chlorinated phenoxyacetic acid herbicides

Effect of ammonium formate as ionizing additive in thermospray liquid chromatography‐mass spectrometry for the determination of triazine, phenylurea and chlorinated phenoxyacetic acid herbicides

Monitoring of 6-chloronicotinic acid in human urine by gas chromatography-tandem mass spectrometry as indicator of exposure to the pesticide imidacloprid

Use of Solvent Adduct Ions To Confirm Structure of Selected Herbicides with Thermospray Liquid Chromatography/Mass Spectrometry

Contact Info

Product

Resources

About