Mass spectrometry of polyurethanes

Crescentini, Tiffany M.; May, Jody C.; McLean, John A.; Hercules, David M.

doi:10.1016/j.polymer.2019.121624

Cited by 23 publications

(19 citation statements)

References 140 publications

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“…10,11 Thermoplastic polyurethane (PU) is a block copolymer that is oen synthesized with diol (so segment), diisocyanate (hard segment), and chain extenders. 12,13 The incompatibility between so and hard segments leads to microphase separation, and the level of microphase separation is closely related to the tensile strength of PU. 14,15 Studies have discussed factors causing microphase separation in PU, such as hydrogen bonds (HBs) 16,17 and the ratio of so and hard segments.…”

Section: Introductionmentioning

confidence: 99%

Properties and degradation of castor oil-based fluoridated biopolyurethanes with different lengths of fluorinated segments

Cheng

Lee

et al. 2019

RSC Adv.

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Section: Introductionmentioning

confidence: 99%

Properties and degradation of castor oil-based fluoridated biopolyurethanes with different lengths of fluorinated segments

Cheng

Lee

et al. 2019

RSC Adv.

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“…PUs are a family of multiblock copolymers containing a carbamate (urethane) group in their backbones [ 7 ]. These polymers are polymerized through step-growth polymerization, in the presence of a catalyst by reacting at least two isocyanates (hard segment) functional groups with hydroxyl or alcohol groups (soft segment).…”

Section: Pu: Chemical Structure and Propertiesmentioning

confidence: 99%

A critical review of fibrous polyurethane-based vascular tissue engineering scaffolds

Karkan

Banimohamad-Shotorbani

Saghati

et al. 2022

J Biol Eng

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Certain polymeric materials such as polyurethanes (PUs) are the most prevalent class of used biomaterials in regenerative medicine and have been widely explored as vascular substitutes in several animal models. It is thought that PU-based biomaterials possess suitable hemo-compatibility with comparable performance related to the normal blood vessels. Despite these advantages, the possibility of thrombus formation and restenosis limits their application as artificial functional vessels. In this regard, various surface modification approaches have been developed to enhance both hemo-compatibility and prolong patency. While critically reviewing the recent advances in vascular tissue engineering, mainly PU grafts, this paper summarizes the application of preferred cell sources to vascular regeneration, physicochemical properties, and some possible degradation mechanisms of PU to provide a more extensive perspective for future research.

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“…Mass spectrometry (MS) is an effective tool for the analysis of synthetic polymers. Recent progress in mass spectrometers in terms of resolution and sensitivity has enabled MS analyses of backbone structure, end group structure, and copolymer composition 1–7 . Matrix‐assisted laser‐induced desorption/ionization (MALDI), a typical soft ionization method, combined with time‐of‐flight MS (TOFMS), is often used for the analysis of various polymers 8–11 .…”

Section: Introductionmentioning

confidence: 99%

“…Recent progress in mass spectrometers in terms of resolution and sensitivity has enabled MS analyses of backbone structure, end group structure, and copolymer composition. [1][2][3][4][5][6][7] Matrix-assisted laser-induced desorption/ionization (MALDI), a typical soft ionization method, combined with time-of-flight MS (TOFMS), is often used for the analysis of various polymers. [8][9][10][11] Although MALDI-TOFMS is a good method for analyzing synthetic polymers, a decrease in analytical efficiency is often observed with an increase in the molecular weight of polymers.…”

Section: Introductionmentioning

confidence: 99%

End group analysis of poly(methylmethacrylate)s using the most abundant peak in electrospray ionization‐ion mobility spectrometry‐tandem mass spectrometry and Fourier transform–based noise filtering

Omae

Ozeki

Kitagawa

et al. 2021

Rapid Comm Mass Spectrometry

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Rationale We recently developed the characterization method for synthetic polymers weighing more than a few tens of kilodalton using electrospray ionization‐ion mobility spectrometry‐tandem mass spectrometry, in which the m/z value of the most abundant peak was used for characterization. However, the identification of the most abundant peak from the isotopic peaks was often difficult due to the background noise. Methods Here, we employed a noise reduction method using Fourier transform (FT) filtering. In the power spectrum obtained using FT of the mass spectrum of the multiple charged analytes, the significant signals in the low‐frequency region and at frequency z are observed for the analytes of z charges. When the signals in both regions were used for inversed FT (i.e., the signals in other regions were zero padded), a noise‐filtered mass spectrum was obtained. Results In the analysis of poly(methylmethacrylate)s weighing 13–17 kDa, mass spectra without noise filtering with relatively high‐intensity noise (than signal) were complicated to identify the most abundant peak. On the contrary, the most abundant peak was clearly identified from the mass spectra after FT‐based noise filtering, and end group composition was estimated successfully. Conclusions The proposed FT‐based noise filtering for the mass spectrum is effective to characterize multiply charged synthetic polymers weighing more than a few tens of kilodalton using electrospray ionization‐ion mobility spectrometry‐tandem mass spectrometry.

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Mass spectrometry of polyurethanes

Cited by 23 publications

References 140 publications

Properties and degradation of castor oil-based fluoridated biopolyurethanes with different lengths of fluorinated segments

Properties and degradation of castor oil-based fluoridated biopolyurethanes with different lengths of fluorinated segments

A critical review of fibrous polyurethane-based vascular tissue engineering scaffolds

End group analysis of poly(methylmethacrylate)s using the most abundant peak in electrospray ionization‐ion mobility spectrometry‐tandem mass spectrometry and Fourier transform–based noise filtering

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