Massive blood transfusion

Michelsen, Torsten; Salmela, L; Tigerstedt, I.; Måkelãinen, A; Linko, K.

doi:10.1097/00003246-198907000-00022

Cited by 13 publications

(3 citation statements)

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“…Literature we found on massive blood transfusion does not mention amounts of this magnitude. [30][31][32] Validation of these records would be needed, however, to confirm if they are errors.…”

Section: Discussionmentioning

confidence: 99%

Blood use by inpatient elderly population in the United States

et al. 2007

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Section: Discussionmentioning

confidence: 99%

Blood use by inpatient elderly population in the United States

et al. 2007

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“…Swyer (6) recorded that 3 out of 6 patients survived in their series after being transfused with 50 units of blood; he found that the patients' preoperative condition was a significant determinant of the outcome. The use of fresh blood, platelets and fresh frozen plasma was needed to prevent significant loss of clotting function (7).…”

Section: Discussionmentioning

confidence: 99%

Hysterectomy, Massive Transfusion and Packing to Control Haemorrhage from Pelvic Veins in the Course of Bilateral Oophorectomy

Edwards¹

1996

Aust NZ J Obst Gynaeco

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“…The reported mortality among MT patients receiving more 20 units of blood has been high mainly because the associated trauma or disease is often severe and carries a morbid prognosis (56,63-651. There are few reports of the extremely voluminous massive transfusions [66,67]. One case report describes a successful outcome after massive transfusion conducted according to strict component therapy (Unpublished data, in press).…”

Section: Extremesmentioning

confidence: 99%

Replacement of Massive Blood Loss

Hiippala

1998

Vox Sanguinis

133

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Treatment of massive blood loss has experienced major changes during the recent decade. The transition towards pure component therapy has been the most significant issue, which has compelled the clinician to revise some of their basic strategies in treatment of massively bleeding patients. The importance of adequate volume resuscitation with crystalloids and colloids is still unrefutable, but the therapy of hemorrhagic derangements has changed. Plasma-poor red cells (RC) are now commonly used instead of whole blood (WB) or packed red blood cells (PRBC) to correct oxygen carrying capacity during massive blood loss. As the plasma content of RC is minimal, deficit of plasma and coagulation factors develops earlier than during transfusion of WB and PRBC. Hypofibrinogenemia develops first followed by other coagulation factor deficits and later by thrombocytopenia. Therefore the use of fresh frozen plasma (FFP) is the primary intervention to treat abnormal bleeding encountered in the replacement of massive blood loss with RC. As the development of thrombocytopenia is a highly individual phenomenon, the transfusion of platelets should be guided by repeatedly determined platelet counts.

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Massive blood transfusion

Cited by 13 publications

References 0 publications

Blood use by inpatient elderly population in the United States

Blood use by inpatient elderly population in the United States

Hysterectomy, Massive Transfusion and Packing to Control Haemorrhage from Pelvic Veins in the Course of Bilateral Oophorectomy

Replacement of Massive Blood Loss

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