Massive Digestive Hemorrhagia Revealing a Gastro-Intestinal Stromal Tumor of the Jejunum

Abstract

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors that originate from Cajal cells located in different sites of the digestive system. They may occur in the entire gastrointestinal tract. They are diagnosed on the basis of the identification of c-kit-positive cells. We report a case of a stromal tumor of the jejunum revealed by a massive digestive hemorrhagia. Surgical resection is the basis of the treatment of GISTs. Imatinib, a tyrosine kinase inhibitor, is a beneficial treatment after surgical resection of high-risk GISTs.

Hypovolemic Shock Revealing a Gastrointestinal Stromal Tumor

“…An abdominal CT scan showed a mass in the gastric region, which was confirmed by upper gastrointestinal exploration. The pathological examination did not reveal any specific findings, but immunohistochemistry confirmed the typical phenotype of CD117/KIT + and DOG-1 + [ 11 ]. Both patients underwent R0 partial gastrectomy, and a simple monitoring plan was decided upon in a multidisciplinary meeting.…”