Massive Eosinophilic Pleural Effusion Preceding Vasculitic Symptoms in Churg-Strauss Syndrome

Tanizawa, Kiminobu; Kaji, Yuji; Tanaka, Eisaku; Inoue, Tetsuro; Sakuramoto, Minoru; Minakuchi, Masayoshi; Maeda, Yuji; Maniwa, Ko; Terada, Kunihiko; Goto, Shunsuke; Takeda, Takumi; Okamoto, Masaki; Hashimoto, Seishu; Noma, Satoshi; Kobashi, Yoichiro; Terada, Yoshio

doi:10.2169/internalmedicine.49.2839

Cited by 6 publications

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“…9 Bronchoalveolar lavage fluid, ascitic fluid, and pericardial fluid specimens also show prominent eosinophils, a non-specific but supportive finding in the diagnosis of EGPA. 7,[10][11][12] Elevated IgE and IgG4 levels are common in EGPA. 13 These laboratory findings may raise the possibility of hyper-IgE syndrome and IgG4-related disease.…”

Section: Role Of Adjunct Testing In Egpamentioning

confidence: 99%

“…Nasal cytology specimens show the presence of eosinophils in the nasal smears of EGPA patients that persist despite long‐term immunosuppressive therapy with systemic steroids 9 . Bronchoalveolar lavage fluid, ascitic fluid, and pericardial fluid specimens also show prominent eosinophils, a non‐specific but supportive finding in the diagnosis of EGPA 7,10‐12 …”

Section: Role Of Adjunct Testing In Egpamentioning

confidence: 99%

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Eosinophilic granulomatosis with polyangiitis: Cutaneous clinical and histopathologic differential diagnosis

2021

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Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, but severe systemic vasculitis that can affect skin and other organ systems. Diagnostic criteria have evolved, and many attempts have been made to classify the vasculitides based on clinical and/or histopathologic features, with an aim to develop standardized criteria.According to the EGPA Consensus Task Force recommendations, EGPA is a syndrome of asthma, eosinophilia, pulmonary infiltrates, and extrapulmonary vasculitis (such as cutaneous involvement with purpura). Histopathologic evidence of vasculitis in EGPA may be associated with eosinophilic infiltration and/or perivascular granulomatous inflammation. We review clinicopathologic criteria of this enigmatic vasculopathy.

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