“…Adverse events were defined as mild (transient effects lasting b 24 hours, eg, crying or discomfort), moderate (requiring medical/general practitioner treatment), or severe (requiring hospital treatment) 16 39 Wilson et al, 41 Zimmerman et al, 52 Humphreys, 21 Alcantara et al, 25,[35][36][37][38] Posadzki and Ernst, 24 Simonian and Staheli, 43 53 Ziv et al, 54 Jacobi et al, 46 L'Ecuyer, 55 Klougart et al, 51 Rageot, 47 40 Miller and Benfield, 26 Doyle, 44 Holla et al, 42 Hayes and Bezilla, 27 Hayden et al, 28 Dobson et al, 22 Pohlman and Holton-Brown, 23 Sawyer et al, 29 Koch et al, 30,31 Bronfort et al, 34 Philippi et al, 32 Rowe et al 33 Manual search of reference lists revealed additional 6 articles: Wiberg et al, 59 Straub et al, 60 Sandell et al, 61 Balon and Aker, 62 Khorshid et al, 63 …”