Massive hemoptysis due to primary mucoepidermoid carcinoma of the lung in a 12-year-old

Toit-Prinsloo, Lorraine Du; Bunn, Belinda Kathleen

doi:10.1007/s12024-016-9782-0

Cited by 2 publications

(3 citation statements)

References 12 publications

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“…A definitive diagnosis requires bronchoscopy and representative biopsy as this tumor exhibits morphological heterogeneity. It can be misdiagnosed as primary non-small cell lung carcinoma if the biopsy is inadequate ( 20 , 21 ). The diagnosis of this rare neoplasm was possible since ours was a pneumonectomy specimen.…”

Section: Discussionmentioning

confidence: 99%

Morphologic spectrum of undetermined causes of hemoptysis- a pathologistÂ’s role

Ganesan

Gurusamy²

2020

TJPATH

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Objective: Hemoptysis is the expectoration of blood or blood-streaked sputum from the tracheobronchial tree. The etiology may derive from nonneoplastic conditions such as infections, chronic pulmonary diseases, and vasculitis or neoplastic causes. Sometimes a definitive cause for hemoptysis cannot be found after ample diagnostic workup. The role of biopsy in such cases is to help the clinician in arriving at the final diagnosis. Diffuse alveolar hemorrhage is the main histopathological finding in hemoptysis and it appears with diffuse chest infiltrates radiologically. Material and Method: A retrospective study of 2 years duration was conducted to identify the morphological spectrum of diseases presenting with hemoptysis. A total of 243 lung biopsies obtained by various methods were retrieved in this study period and 20 cases with hemoptysis of undetermined etiology were detected. Results: Based on imaging and histopathology findings, the etiological causes of hemoptysis were divided into hemoptysis with and without capillaritis or due to tumor/tumor-like lesions and due to miscellaneous conditions. The most common etiology was vasculitis followed by infections. Conclusion: Histopathology helps to detect the etiology, particularly in cases of hemoptysis due to non-immunologic causes. In immunologic cases, histopathological findings may support the diagnosis in correlation with the clinical/imaging features.

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Section: Discussionmentioning

confidence: 99%

Morphologic spectrum of undetermined causes of hemoptysis- a pathologistÂ’s role

Ganesan

Gurusamy²

2020

TJPATH

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“…It is an extremely rare malignant neoplasm of the lung that accounts for approximately 0.1–0.2% of all lung malignancies . PMEC is a salivary gland‐type tumor of the lung, deriving from the minor salivary glands of the tracheobronchial tree and has been reported to occur over an age range of 3–78 years . Compared to other salivary gland‐type tumors of the lung, there is no gender predilection in PMEC .…”

Section: Introductionmentioning

confidence: 99%

“…[3][4][5][6][7] PMEC is a salivary gland-type tumor of the lung, 5,8 deriving from the minor salivary glands of the tracheobronchial tree 9 and has been reported to occur over an age range of 3-78 years. 3,10,11 Compared to other salivary gland-type tumors of the lung, there is no gender predilection in PMEC. 5,12 According to the 2015 World Health Organization classification of lung cancer, PMEC is a mucoepidermoid carcinoma.…”

Section: Introductionmentioning

confidence: 99%

Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

Guo

Liu

et al. 2017

Thoracic Cancer

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Primary pulmonary mucoepidermoid carcinoma (PMEC) is extremely rare. Herein, we report a case of a 71‐year‐old male patient with high‐grade PMEC involving the right upper lobe that was successfully resected via lobectomy. As a result of invasion into the pleural and paratracheal lymph nodes, four cycles of adjuvant chemotherapy with paclitaxel and carboplatin were administered. There were no signs of relapse during 10 months of follow‐up. Furthermore, we reviewed the literature and summarized the surgical approaches, prognostic factors, and underlying genetic mechanisms of PMEC, which will benefit clinical treatment.

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Massive hemoptysis due to primary mucoepidermoid carcinoma of the lung in a 12-year-old

Cited by 2 publications

References 12 publications

Morphologic spectrum of undetermined causes of hemoptysis- a pathologistÂ’s role

Morphologic spectrum of undetermined causes of hemoptysis- a pathologistÂ’s role

Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

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