Massive pleural effusion: an unusual presentation of Castleman's disease

Reynolds, S. P.; Gibbs, A. R.; Weeks, R. A.; Adams, Hume; Davies, B H

doi:10.1183/09031936.93.05091150

Cited by 22 publications

(1 citation statement)

References 17 publications

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“…Rarely thoracic CD can arise from other locations, including the pleura, pericardium, intercostal space, and lung. Pleural CD may present as a well-defined interlobar mass or massive pleural effusion [14] Pericardial CD may present as a pericardial mass looking like a pericardial cyst [15] . Intercostal CD may manifest as an extrapulmonary mass with rib erosion [16] MCD can present as diffuse reticulonodular infiltrates , ascites with hepatosplenomegaly.…”

Section: Discussionmentioning

confidence: 99%

Castlemans Disease – Presenting with Recurrent Pleuropericardial Effusions- Mimicking Tuberculosis

2023

IJCR

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Castleman disease (CD) is an uncommon heterogeneous group of lymphoproliferative disorders which can affect the lymph nodes of the neck, chest, abdomen and pelvis. It was first described by Castleman, in 1954, known as benign mediastinal lymph node hyperplasia, which was histologically similar to thymoma of unknown cause. [1] It is divided into unicentric (localized ) Castleman disease (UCD) and multicentric ( generalized) Castleman disease (MCD) based on the number of lymph nodes involved. Castleman disease has varied presentations. Clinically it can present as localized masses, or localized lymph node enlargement. Symptoms can result from compression effects of the enlarged lymph nodes and in asymptomatic patients it can be an incidental finding on radiological imaging. It can also present as diffuse lymphadenopathy with severe systemic symptoms . Rarely it presents with pleuro-pericardial effusions . We present a case of a; young gentleman presenting with anorexia, weight loss and night sweats . He had large exudative pleural effusion with pericardial effusion leading to constrictive pericarditis .He was started on ATT empirically, which was later stopped due to poor response . Extensive radiological work revealed multi loculated pleural effusion and multiple lymph nodes in the axillary and cervical area . Excisional Biopsy of the lymph nodes revealed Castleman disease .

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Section: Discussionmentioning

confidence: 99%

Castlemans Disease – Presenting with Recurrent Pleuropericardial Effusions- Mimicking Tuberculosis

2023

IJCR

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Localized Castleman's disease and nephrotic syndrome not responsive to resection plus colchicine therapy

Derici

Arınsoy

Ataoğlu

et al. 2002

Annals of Hematology

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We describe one patient with localized Castleman's disease (CD) of the mixed hyaline vascular and plasma cell type located at the mesentery of the small bowel, associated with systemic amyloidosis and nephrotic syndrome. A true nephrotic syndrome has rarely been reported in patients with CD. In the literature, it has been suggested that clinical and laboratory manifestations generally improved after surgical resection of the tumor. However, in our case, clinical and laboratory findings did not regress after operation followed by colchicine therapy.

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Chest wall Castleman's disease: CT and MRI findings

et al. 2006

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Castleman's disease is an usually benign lymphoid tumor of uncertain etiology that generally appears as a solitary mediastinal mass. We present a case of Castleman's disease in the right chest wall of a 60-year-old woman. Magnetic resonance imaging showed a well-defined, oval mass that was early enhanced on T1-weighted images. The mass was diagnosed by percutaneous core needle biopsy with computed tomography guidance. The patient has remained well for 5 years without an increase in tumor size. We also summarize the international literature.

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Massive pleural effusion: an unusual presentation of Castleman's disease

Cited by 22 publications

References 17 publications

Castlemans Disease – Presenting with Recurrent Pleuropericardial Effusions- Mimicking Tuberculosis

Castlemans Disease – Presenting with Recurrent Pleuropericardial Effusions- Mimicking Tuberculosis

Localized Castleman's disease and nephrotic syndrome not responsive to resection plus colchicine therapy

Chest wall Castleman's disease: CT and MRI findings

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