“…In a double-blind, placebo-controlled study of 30 adults with autism, fluvoxamine significantly reduced aggression, maladaptive behavior, and obsessive-compulsive symptoms and improved certain aspects of social relatedness, most notably language use. 5 There may also be a role for atypical neuroleptic agents, particularly risperidone, a potent serotonin-2A-receptor antagonist. Preliminary analysis of data from a double-blind, placebo-controlled study of risperidone in adults with autism, performed at this institution, To the Editor: In her review Dr. Rapin states that "children with autism may be affectionate, but .…”