Massives lokalisiertes Lymphödem einer extrem fettleibigen Patientin

Váňa, Juraj; Adamicová, Katarína; Haluska, P.; Celec, J

doi:10.1007/s00104-001-0370-8

Cited by 5 publications

(5 citation statements)

References 4 publications

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“…Based on the clinical history, the provided clinical photograph, and the photomicrographs, these "tumors" would appear to be indisputable examples of massive localized lymphedema of the morbidly obese, a distinctive pseudoneoplasm first reported by Farshid and Weiss 2 in The American Journal of Surgical Pathology in 1998 and subsequently reported in a number of additional publications. [3][4][5][6][7][8][9][10][11][12] As in the case presented by Bae et al, 1 massive localized lymphedema is almost always seen in morbidly obese patients, where it presents as giant, pendulous masses of the medial thighs. On gross pathologic examination, massive localized lymphedema displays striking dermal thickening and fibrosis with prominent stromal edema and expansion of the fibrous septa between the individual fat lobules.…”

Section: Comments and Opinionsmentioning

confidence: 99%

Myopathy Induced by Antimalarial Agents: The Relevance of Screening Muscle Enzyme Levels

Kalajian¹,

Callen²

2009

Arch Dermatol

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Comment. Scalp dermoscopy or trichoscopy is a useful noninvasive adjunct to the pediatric scalp examination that allows the rapid capture of high-resolution images for in vivo evaluation. We describe a novel normal scalp finding in children and document the presence of dermoscopic patterns previously described in adults. Dirty dots, which present on the scalp as clumped and haphazardly arrayed particulate debris and loose fibers of various colors, were most commonly found in the intermediate age group (83% of those aged 9 months to 10 years; 10 of 12), and not at all in younger or older age groups. Two intermediate-aged subjects reevaluated 3 years after their initial examination demonstrated an improvement with age. The experience of 1 of us (A.T.) suggests that dirty dots are rarely if ever seen on the adult scalp. Bacterial and fungal cultures from the scalp of 2 subjects withdirtydotswerenegative.Dirtydotswerereadilyremoved by shampoo, but reaccumulated as early as 1 day afterwards. Unlike dirty dots, the yellow scale of seborrheic dermatitis was more common in younger and older children. We present dirty dots as a novel and unique dermoscopic finding of the normal scalp examination in prepubertal children. Dirty dots likely represent nonmicrobial environmental particles and should not be confused with cadaverized hairs or other abnormal trichoscopic structures. Given the negative correlation between the presence of dirty dots and seborrheic dermatitis in our series, we postulate that the relative decrease in sebaceous activity in prepubertal children may lead to an inability to repel particulate debris from exogenous environmental sources. Future studies to elucidate the potential relationship between dirty dots and sebaceous activity will be of interest.

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Section: Comments and Opinionsmentioning

confidence: 99%

Myopathy Induced by Antimalarial Agents: The Relevance of Screening Muscle Enzyme Levels

Kalajian¹,

Callen²

2009

Arch Dermatol

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“…The histopathological diagnosis is evidenced by widespread interstitial edema, associated with reactive fibroblast proliferation, acanthosis and dermal sclerosis, vascular and lymphatic ectasia, with inflammation. Macroscopically, the hardened tumor mass and the skin with the "orange peel" appearance feature the frequent pachydermia that accompany MLL 4,[7][8][9][10] . Any lymphatic obstruction may precipitate regional lymphedema.…”

Section: Results Results Results Resultsmentioning

confidence: 99%

“…Within this context, in all our patients the predisposing factor was obesity and the described etiopathogenic mechanism was triggering by infection, due to favorable local conditions. However, one cannot rule out that the same lymphatic drainage disorder is a result of obesity alone, running parallel to the two theories previously mentioned 7,10 . The possibility of recurrence cannot be overlooked 4,7,8,10 .…”

Section: A B C Dmentioning

confidence: 96%

“…However, one cannot rule out that the same lymphatic drainage disorder is a result of obesity alone, running parallel to the two theories previously mentioned 7,10 . The possibility of recurrence cannot be overlooked 4,7,8,10 . The presence of the pedicle at the base of the tumor and no involvement of the deep layers below the muscle-aponeurotic fascia generally facilitate surgical resection.…”

Section: A B C Dmentioning

confidence: 96%

“…Beside this, the huge tumor mass hinders local hygiene, thus allowing accumulation of debris and recurrent infectious episodes of cellulitis, worsening symptoms 2,6,7 . This paper assesses the importance of the surgical treatment of massive localized lymphedema in severely obese patients.…”

Section: Introduction Introduction Introduction Introduction Introducmentioning

confidence: 99%

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Results of surgical treatment of massive localized lymphedema in severely obese patients

Júnior

Modolin

Rocha

et al. 2014

Rev. Col. Bras. Cir.

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OBJECTIVE: to evaluate the importance of treatment of deformities caused by massive localized lymphedema (MLL) in the severely obese. METHODS: in a period of seven years, nine patients with morbid obesity and a mean age of 33 years underwent surgical resection of massive localized lymphedema with primary synthesis. This is a retrospective study on the surgical technique, complication rates and improved quality of life. RESULTS: all patients reported significant improvement after surgery, with greater range of motion, ambulation with ease and more effective hygiene. Histological analysis demonstrated the existence of a chronic inflammatory process marked by lymphomonocitary infiltrate and severe tissue edema. We observed foci of necrosis, formation of microabscesses, points of suppuration and local fibrosis organization, and pachydermia. The lymphatic vessels and some blood capillaries were increased, depicting a framework of linfangiectasias. CONCLUSION: surgical treatment of MLL proved to be important for improving patients' quality of life, functionally rehabilitating them and optimizing multidisciplinary follow-up of morbid obesity, with satisfactory surgical results and acceptable complication rates, demonstrating the importance of treatment and awareness about the disease.

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Giant Subcutaneous Tumors on the Thighs

Folpe¹

2009

Arch Dermatol

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Massives lokalisiertes Lymphödem einer extrem fettleibigen Patientin

Abstract: Soft tissue tumors are commonly encountered in all surgical departments. The authors present a case of a very rare large tumor lesion, with macroscopic signs of liposarcoma.

Cited by 5 publications

References 4 publications

Myopathy Induced by Antimalarial Agents: The Relevance of Screening Muscle Enzyme Levels

Myopathy Induced by Antimalarial Agents: The Relevance of Screening Muscle Enzyme Levels

Results of surgical treatment of massive localized lymphedema in severely obese patients

Giant Subcutaneous Tumors on the Thighs

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