Mast cells in nasal polyps

Free and cell bound IgE in nasal polyps

“…This was not found later on EM and probably was due to the fact that spindle-shaped mast cells were less granulated and may have become distorted during preparation (Drake-Lee et al, in press). Donovan (1971) noted similar types of mast cells but could find no correlation between mast cells, eosinophils or IgE levels. He expected to find few mast cells with large numbers of eosinophils since the granules are lost during release.…”