Mastoiditis complicated with Gradenigo syndrome and a hypertrophic pachymeningitis with consequent communicating hydrocephalus

Bravo, Dina; Machová, Hana; Hahn, Aleš; Marková, Hana; Otruba, Lukáš; Mandys, Václav; Houšťava, Ladislav; Kalvach, Pavel

doi:10.1080/00016480500475583

Cited by 8 publications

(1 citation statement)

References 4 publications

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“…Bravo et al 121 reported mastoiditis complicated with Gradenigo's syndrome and a hypertrophic pachymeningitis with consequent communicating hydrocephalus. Documented by the development of clinical findings, magnetic resonance imaging, cerebrospinal fluid changes, histopathology findings, otosurgical intervention, and finally the insertion of a ventriculo‐peritoneal shunt, the case illustrates a gradual development of pachymeningitis with consequent hydrocephalus and intracranial hypertension.…”

Section: Discussionmentioning

confidence: 99%

Panel 8: Complications and Sequelae

Jung¹,

Alper

Hellström³

et al. 2013

Otolaryngol.--head neck surg.

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Section: Discussionmentioning

confidence: 99%

Panel 8: Complications and Sequelae

Jung¹,

Alper

Hellström³

et al. 2013

Otolaryngol.--head neck surg.

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Anti-neutrophil cytoplasmic antibody-associated hypertrophic cranial pachymeningitis and otitis media: a review of literature

Peng

Yang

et al. 2018

Eur Arch Otorhinolaryngol

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Background and objectiveIt has been recognized that anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides may lead to hypertrophic pachymeningitis (HP) or intractable otitis media (OM). To our knowledge, few cases of coexistent ANCA-related HP and OM have been described previously. To increase awareness of this disease, we reviewed the literature describing patients with HP and intractable OM in a population with AAV to guide clinical decision making for otolaryngologists.Methods PubMed was searched with the following terms: ANCA-associated vasculitis, otitis media, and hypertrophic pachymeningitis. Only patients with concomitant AAV, OM and HP were considered and included in this review.ResultsA total of 243 articles were reviewed, and of these, 6 met inclusion criteria. Headache, cranial polyneuropathy, and intractable OM with effusion or granulation were common. Serum MPO–ANCA positivity was most common in Asian patients. Almost all patients had dural mater thickening on gadolinium-enhanced magnetic resonance imaging of the brain. Corticosteroids plus an immunosuppressant was more effective and most patients had improved hearing after treatment, but approximately 50% of subjects had disease relapse.ConclusionIn this review, we summarized the current knowledge on the clinical features, diagnosis, treatment, and pathogenesis of this disease. We should carefully detect the potential cases of ANCA-related HP and OM in patients with intractable OM, HP, or AAV, and make the optimal treatment plan to avoid long-term neurological complications and irreversible hearing loss. Furthermore, due to an increased possibility of relapse, close follow-up, including a hearing test, ANCA titers, imaging examination, and detection of toxic and side effects of immunosuppressive therapy, are necessary.

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Otitis media aguda y sus complicaciones agudas

Alegría¹,

Catalá²

2009

Tratado De Otorrinolaringología Y Patología Cervicofacial

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Mastoiditis complicated with Gradenigo syndrome and a hypertrophic pachymeningitis with consequent communicating hydrocephalus

Cited by 8 publications

References 4 publications

Panel 8: Complications and Sequelae

Panel 8: Complications and Sequelae

Anti-neutrophil cytoplasmic antibody-associated hypertrophic cranial pachymeningitis and otitis media: a review of literature

Otitis media aguda y sus complicaciones agudas

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