Matched-Pair Analysis of Survival of Never Smokers and Ever Smokers With Squamous Cell Carcinoma of the Head and Neck

Pytynia, Kristen B.; Grant, Jonathan R.; Etzel, Carol J.; Roberts, Dianna B.; Wei, Qingyi

doi:10.1200/jco.2004.02.133

Cited by 85 publications

(67 citation statements)

References 27 publications

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“…* This method was chosen because it accommodates a non-normal distribution of events, analysis of matched intervention-control pairs, and a large proportion of patients with missing data for the time of an event (many patients did not have a subsequent visit during the 365-day follow-up period). 16 The first step was to create a basic model. "Treatment" was the main covariate in this model; gender, race, reference year, and insurance status were added to control for their effects.…”

Section: Discussionmentioning

confidence: 99%

A Matched-Cohort Evaluation of a Bedside Asthma Intervention for Patients Hospitalized at a Large Urban Children’s Hospital

Davis

Benson²,

Cooney³

et al. 2011

J Urban Health

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Emergency care and hospitalizations account for 36% of asthma-related medical expenses for children. National asthma guidelines emphasize the need for asthma self-management education at multiple points of care, including the hospital, to help prevent acute exacerbations. The integration of a bedside asthma education program into discharge planning at a busy urban children's hospital aimed to reduce repeat emergency department (ED) visits and hospitalizations by educating the community's highest-risk children and their families about asthma. A trained respiratory professional provided 45 minutes of individualized bedside education to families at the hospital and one follow-up support phone call within 3 weeks after discharge. Children receiving the intervention were matched to a control group of children not receiving the intervention by age and 2 markers of past utilization using data obtained from hospital records. Repeat ED utilization was analyzed using a Cox proportional hazards model controlling for sex, residence, race or ethnicity, and year. Compared to 698 matched controls, no significant improvement was observed in the 698 intervention participants or any subgroups followed for 12 months after the intervention.

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Section: Discussionmentioning

confidence: 99%

A Matched-Cohort Evaluation of a Bedside Asthma Intervention for Patients Hospitalized at a Large Urban Children’s Hospital

Davis

Benson²,

Cooney³

et al. 2011

J Urban Health

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“…In one study, head and neck cancer patients with any history of smoking (former or current) were found to have not only lower rates of survival but also lower rates of disease-specific survival and recurrence-free survival compared with patients who had never smoked. 28 In a study of patients with Stage I nonsmall-cell lung cancer, Fujisawa and colleagues 29 found a significantly higher overall survival rate at 10 years for patients reporting less than 30 pack-years of cigarette smoking (83.0%) than for patients with a history of more than 30 pack-years (36.7%).…”

Section: Impact Of Smoking and Smoking Cessation On Survival Ratesmentioning

confidence: 99%

Successes and failures of the teachable moment

Gritz

Fingeret

Vidrine

et al. 2005

Cancer

326

294

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Objective We utilized the amyloid imaging ligand Pittsburgh Compound B (PiB) to determine the presence of Alzheimer's disease (AD) pathology in different mild cognitive impairment (MCI) subtypes and to relate increased PiB binding to other markers of early AD and longitudinal outcome. Methods Twenty‐six patients with MCI (13 single‐domain amnestic‐MCI [a‐MCI], 6 multidomain a‐MCI, and 7 nonamnestic MCI) underwent PiB imaging. Twenty‐three had clinical follow‐up (21.2 ± 16.0 [standard deviation] months) subsequent to their PiB scan. Results Using cutoffs established from a control cohort, we found that 14 (54%) patients had increased levels of PiB retention and were considered “amyloid‐positive.” All subtypes were associated with a significant proportion of amyloid‐positive patients (6/13 single‐domain a‐MCI, 5/6 multidomain a‐MCI, 3/7 nonamnestic MCI). There were no obvious differences in the distribution of PiB retention in the nonamnestic MCI group. Predictors of conversion to clinical AD in a‐MCI, including poorer episodic memory, and medial temporal atrophy, were found in the amyloid‐positive relative to amyloid‐negative a‐MCI patients. Longitudinal follow‐up demonstrated 5 of 13 amyloid‐positive patients, but 0 of 10 amyloid‐negative patients, converted to clinical AD. Further, 3 of 10 amyloid‐negative patients “reverted to normal.” Interpretation These data support the notion that amyloid‐positive patients are likely to have early AD, and that the use of amyloid imaging may have an important role in determining which patients are likely to benefit from disease‐specific therapies. In addition, our data are consistent with longitudinal studies that suggest a significant percentage of all MCI subtypes will develop AD. Ann Neurol 2009;65:557–568

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“…These groups of patients need to be studied further, for the possible factors that induce molecular changes in the epithelium which may proceed to dysplasia and cancer. Some of the risk factors observed in the past are viral association particularly infection with Human papilloma virus (HPV), Infections with microorganism such as candida, Syphilis, Poor oral hygiene, Tooth loss due to aggressive periodontitis, And a diet low in fresh fruits and vegetables 8 . Prevalence ofHPV-16 is reportedbe high in Oral Squamous Cell Carcinoma and the data concerning the prevalence of HPV in the oral cavity is not similar, ranging from 2.6-98% 9 .…”

Section: Discussionmentioning

confidence: 99%

Oral squamous cell carcinoma - A case report

Nathan¹,

Asokan²,

Anandi³

et al. 2017

Int. J. Curr. Res. Biol. Med

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Oral Cancer is the 6 th most common cancer globally, More than 90% cases are squamous cell carcinoma 1 . The incidence of OSCC in Southeast Asia and South Central Asia is reported to be more with habits like Pan chewing, tobacco chewing and diet low in fresh vegetables and fruits 2 . The common predisposing factors in developed countries are tobacco and alcohol 3 . Here we present a case report of OSCC with absence of the common predisposing factors.

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Matched-Pair Analysis of Survival of Never Smokers and Ever Smokers With Squamous Cell Carcinoma of the Head and Neck

Cited by 85 publications

References 27 publications

A Matched-Cohort Evaluation of a Bedside Asthma Intervention for Patients Hospitalized at a Large Urban Children’s Hospital

A Matched-Cohort Evaluation of a Bedside Asthma Intervention for Patients Hospitalized at a Large Urban Children’s Hospital

Successes and failures of the teachable moment

Oral squamous cell carcinoma - A case report

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