Material Analysis and Optical Quality Assessment of Opacified Hydrophilic Acrylic Intraocular Lenses After Pars Plana Vitrectomy

Yildirim, Timur M.; Auffarth, Gerd U.; Łabuz, Grzegorz; Bopp, Silvia; Son, Hyeck-Soo; Khoramnia, Ramin

doi:10.1016/j.ajo.2018.06.002

Cited by 54 publications

(79 citation statements)

References 22 publications

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“…The optical performance of the IOLs was evaluated using the optical bench OptiSpheric IOL Pro II (Trioptics GmbH, Germany), as described in previous studies [13][14][15][16][17][18][19]. Its measurement principles adhere to the guidelines governed by the International Standard Organization (ISO) 11979-2 [20] and 11979-9 [21,22] and it thus includes a model cornea (spherical aberration: 0.28 μm) and a model eye containing a balanced salt solution with a refractive index of 1.336 at 25˚C.…”

Section: Optical Quality Evaluationmentioning

confidence: 99%

Ray propagation imaging and optical quality evaluation of different intraocular lens models

et al. 2020

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Ray propagation visualization and optical performance analysis of four different intraocular lenses (IOLs) Methods In this laboratory study, four IOLs with different optical designs were assessed: a monofocal AcrySof IQ SN60WF [Alcon], a diffractive-refractive bifocal AcrySof IQ Restor SN6AD1 [Alcon], a diffractive trifocal AcrySof IQ PanOptix TFNT00 [Alcon], and a diffractive extended-depth-of-focus (EDOF) Symfony ZXR00 [Johnson&Johnson]. An experimental setup with a water bath containing 0.01% fluorescein solution and monochromatic green laser light (532 nm) was used to visualize the propagation of light rays. Also, the optical performance of the IOLs was evaluated by measuring the modulation transfer function (MTF) values at a pupil sizes of 3.0 and 4.5 mm on the optical bench OptiSpheric ® IOL PRO II (Trioptics GmbH, Germany). Results Both the diffractive-refractive bifocal IOL and the EDOF IOL showed two defined foci for distance and near vision. In the diffractive trifocal IOL, three distinct foci for distance, intermediate, and near vision could be visualized. Conclusions The ray propagation visualization technique allows a qualitative assessment and comparison of light energy distribution between different IOL models. The measured Through-Focus Response (TFR) quantitatively confirmed the evaluated ray propagation behavior.

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Section: Optical Quality Evaluationmentioning

confidence: 99%

Ray propagation imaging and optical quality evaluation of different intraocular lens models

et al. 2020

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“…Lenses made of hydrophobic acrylate show a lower tendency to develop posterior capsule opacification in comparison to those made of polymethyl methacrylate (PMMA) or hydrophilic acrylate [12]. Complications associated with hydrophilic acrylate lenses like IOL calcification have not been described in hydrophobic IOL material [13]. Hydrophobic acrylate IOLs can be cost-effectively produced and offer good handling during small incision cataract surgery [4].…”

Section: Discussionmentioning

confidence: 99%

Glistening formation in a new hydrophobic acrylic intraocular lens

et al. 2020

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Background: The formation of fluid-filled microvacuoles, termed glistenings, is a common complication of intraocular lenses (IOLs) made from hydrophobic acrylate. Using our well-established in-vitro laboratory method, we evaluated a new IOL material's resistance to glistening formation. Methods: An in-vitro stress test for glistening induction was performed on 20 samples of hydrophobic acrylic IOLs: ten of the new Eyecryl ASHFY600 (Biotech Vision Care, Ahmedabad, India) compared with ten samples of AcrySof IQ SN60WF (Alcon, Fort Worth, USA). The number of microvacuoles per square millimetre (MV/mm 2) was evaluated in five sections of each IOL. The results for each model were compared and rated on a modified Miyata Scale for grading glistening severity. Results: In all cases, glistening number was higher in the central section of the IOL optic than in the periphery. Mean number of MV/mm 2 was highest in the central part of the AcrySof IQ SN60WF, with 41.84 (±27.67) MVs/mm 2. The lowest number of glistenings was found in the five sections of the Eyecryl ASHFY600 with 0.52 (±0.24) MVs/ mm 2. Mean value of the Eyecryl ASHFY600 IOL, using the Miyata Scale, was Zero. Conclusion: In this in-vitro laboratory study, the new hydrophobic acrylic IOL showed a high resistance to microvacuole formation. Results from this in-vitro study suggest that glistening numbers will be low in clinical use in the Eyecryl ASHFY600.

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“…[11] Complications associated with hydrophilic acrylate lenses like IOL calcification have not been described in hydrophobic IOL material. [12] Hydrophobic acrylate IOLs can be cost-effectively produced and offer good handling during small incision cataract surgery. [4] Despite these benefits, hydrophobic acrylic IOLs are prone to develop glistenings.…”

Section: Discussionmentioning

confidence: 99%

Glistening formation in a new hydrophobic acrylic intraocular lens

Yildirim

Fang

Schickhardt

et al. 2020

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Background: The formation of fluid-filled microvacuoles, termed glistenings, is a common complication of intraocular lenses (IOLs) made from hydrophobic acrylate. Using our well-established in-vitro laboratory method, we evaluated a new IOL material’s resistance to glistening formation.Methods: An in-vitro stress test for glistening induction was performed on twenty samples of hydrophobic acrylic IOLs: ten of the new Eyecryl ASHFY600 (Biotech Vision Care, Ahmedabad, India) compared with ten samples of AcrySof IQ SN60WF (Alcon, Fort Worth, USA). The number of microvacuoles per square millimetre (MV/mm2) was evaluated in five sections of each IOL. The results for each model were compared and rated on the Miyata Scale for grading glistening severity.Results: In all cases, glistening number was higher in the central section of the IOL optic than in the periphery. Mean number of MV/mm2 was highest in the central part of the AcrySof IQ SN60WF, with 41.84 (±27.67) MVs/mm². The lowest number of glistenings was found in the five sections of the Eyecryl ASHFY600 with 0.52 (±0.24) MVs/mm². Mean value of the Eyecryl ASHFY600 IOL, using the Miyata Scale, was Zero.Conclusion: In this in-vitro laboratory study, the new hydrophobic acrylic IOL showed a high resistance to microvacuole formation. Results from this in-vitro study suggest that glistening numbers will be low in clinical use in the Eyecryl ASHFY600.

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Material Analysis and Optical Quality Assessment of Opacified Hydrophilic Acrylic Intraocular Lenses After Pars Plana Vitrectomy

Cited by 54 publications

References 22 publications

Ray propagation imaging and optical quality evaluation of different intraocular lens models

Ray propagation imaging and optical quality evaluation of different intraocular lens models

Glistening formation in a new hydrophobic acrylic intraocular lens

Glistening formation in a new hydrophobic acrylic intraocular lens

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