Materials: Cannulas, Pumps, Oxygenators

Borrelli, Umberto; Costa, Cristina

doi:10.1007/978-88-470-5427-1_6

Cited by 2 publications

(3 citation statements)

References 13 publications

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“…Therefore, PMP membranes have a longer operating life than PP membranes. Furthermore, gas permeability for oxygen and carbon dioxide in PMP membranes is excellent, with the gas exchange capability remaining equivalent to that of microporous membranes [66].…”

Section: Polymethylpentene-based Membrane Oxygenatormentioning

confidence: 96%

“…In the early 2000s, a new generation of polymethylpentene (PMP) membrane oxygenators has been introduced to avoid complications linked to HF oxygenators, such as plasma leakage. Different from PPHFs, which are typically microporous, PMPHFs have an asymmetric pore structure with a dense outer skin that provides complete physical separation between the blood and the gas phases, thus avoiding plasma leakage [66,67]. In addition, the asymmetric structure of the PMPHF also allows for efficient gas exchange to take place for extended periods [68,69].…”

Section: Polymethylpentene-based Membrane Oxygenatormentioning

confidence: 99%

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Membrane Oxygenator for Extracorporeal Blood Oxygenation

Ratnaningsih

Aryanti

Himma

et al. 2021

J. Eng. Technol. Sci.

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Extracorporeal blood oxygenation has become an alternative to supply O2 and remove CO2 from the bloodstream, especially when mechanical ventilation provides insufficient oxygenation. The use of a membrane oxygenator offers the advantage of lower airway pressure than a mechanical ventilator to deliver oxygen to the patient’s blood. However, research and development are still needed to find appropriate membrane materials, module configuration, and to optimize hydrodynamic conditions for achieving high efficient gas transfer and excellent biocompatibility of the membrane oxygenator. This review aims to provide a comprehensive description of the basic principle of the membrane oxygenator and its development. It also discusses the role and challenges in the use of membrane oxygenators for extracorporeal oxygenation on respiratory and cardiac failure patients.

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Section: Polymethylpentene-based Membrane Oxygenatormentioning

confidence: 96%

Section: Polymethylpentene-based Membrane Oxygenatormentioning

confidence: 99%

Membrane Oxygenator for Extracorporeal Blood Oxygenation

Ratnaningsih

Aryanti

Himma

et al. 2021

J. Eng. Technol. Sci.

View full text Add to dashboard Cite

show abstract

“…Polymethylpentene is one of the materials practically applied as an asymmetric gas exchange membrane for membrane oxygenator. The polymethylpentene asymmetric membrane has no plasma leakage and has durability to withstand use for 2-3 weeks [44][45][46].…”

Section: Asymmetric Membranementioning

confidence: 99%

Development of a Membrane Oxygenator for Long-Term ECMO Support Using Fine Silicone Hollow Fiber

Yokoi,

Anraku,

Takai

et al. 2024

Evolving Therapies and Technologies in Extracorporeal Membrane Oxygenation [Working Title]

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A membrane oxygenator is an artificial organ that temporarily replaces the gas exchange functions of the lungs during medical procedures such as open-heart surgery or as respiratory support for patients with severe respiratory or cardiopulmonary failure. It can also serve as a bridge to lung transplantation. For long-term use of several months, the oxygenator must have durability and safety. Silicone rubber was focused on for its excellent gas permeability. A membrane oxygenator using fine silicone hollow fiber membranes was developed. This membrane has high permeability and no plasma leakage, making it potentially suitable for long-term lung support. An in vitro experiment with bovine blood evaluated the developed device. With a blood flow rate of 3 L/min, the oxygen transfer rate of the oxygenator with 2 m2 membrane area was about 36% higher, and the carbon dioxide transfer rate about 28% higher, than the 1 m2 membrane area oxygenator. However, the pressure drop increased with larger membrane area. The goal is to develop a silicone hollow fiber membrane oxygenator that can achieve low pressure drop and withstand long-term use.

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Materials: Cannulas, Pumps, Oxygenators

Cited by 2 publications

References 13 publications

Membrane Oxygenator for Extracorporeal Blood Oxygenation

Membrane Oxygenator for Extracorporeal Blood Oxygenation

Development of a Membrane Oxygenator for Long-Term ECMO Support Using Fine Silicone Hollow Fiber

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