2002
DOI: 10.1034/j.1600-0412.2002.810803.x
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Maternal and fetal morbidity in pregnancies of Norwegian and Swedish women with cystic fibrosis

Abstract: Women with cystic fibrosis with mild to moderate disease may safely go through pregnancy. In those with severe disease, preterm delivery is common. A team approach is necessary to provide the best medical care for pregnant women with cystic fibrosis.

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Cited by 50 publications
(12 citation statements)
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References 41 publications
(38 reference statements)
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“…However, the pulmonary function of our patients (median FEV 1 of 56%) was lower than in prior obstetric case series (61 -76% predicted) [6,8,10 -12]. Unlike our case series, in these prior studies only a small minority of patients had severe pulmonary impairment (defined as less than 50% predicted normal) [6,8,10,11,16]. Thus, with the increased survival of CF patients, and improved obstetric care, CF women with severe disease are choosing to reproduce.…”
Section: Discussioncontrasting
confidence: 82%
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“…However, the pulmonary function of our patients (median FEV 1 of 56%) was lower than in prior obstetric case series (61 -76% predicted) [6,8,10 -12]. Unlike our case series, in these prior studies only a small minority of patients had severe pulmonary impairment (defined as less than 50% predicted normal) [6,8,10,11,16]. Thus, with the increased survival of CF patients, and improved obstetric care, CF women with severe disease are choosing to reproduce.…”
Section: Discussioncontrasting
confidence: 82%
“…Almost half of our patients were in nutritional failure at the time of conception and thus are representative of the U.S. CF population. The median weight gain of the patients in our series (10.4 kg) was as high as any prior CF population series (lowest in France, 5.7 kg and equally high in Norway and Sweden, 10.4 kg) [6,8,10,11]. With aggressive oral supplementation and with TPN in a third of our patients, all delivered fetuses of appropriate weight for gestational age.…”
Section: Discussionmentioning
confidence: 63%
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“…Four recent cohort studies have clarified the frequency and outcomes of pregnancy in patients with CF [28][29][30][31]. These studies represent data from four countries (United States, France, Norway, and Sweden).…”
Section: Additional Studiesmentioning
confidence: 99%