Maternal and foetal outcome following pregnancy after intrathoracic organ transplantation: single centre experience in 21 patients

Pregnancy care in solid organ transplant recipients

“…Rates of cesarean birth are comparable to other organ transplant recipients at 42%. Miscarriage rates are 24%–26%, which are higher than in other transplant recipients 26,57 . Pregnant lung transplant patients have a higher risk of neonatal complications.…”

“…Although rates of graft rejection and 2‐year graft loss from National Transplantation Pregnancy Registry data in 2003 (14 patients) were as high as 27% and 21%, respectively, 56 current data (35 recipients, 48 pregnancies) suggest that the rates are lower, with rejection being 15% and 2‐year graft loss being 6%. A study of 29 pregnancies found the rejection rate to be 10.34% 57 . Long‐term effects on graft function in this population are still not adequately studied.…”

“…Miscarriage rates are 24%-26%, which are higher than in other transplant recipients. 26,57 Pregnant lung transplant patients have a higher risk of neonatal complications. The live-birth rate is the lowest among transplant recipients with rates ranging from 42% to 62% reported 26,54,57 and the preterm birth rate is 58%.…”

“…26,57 Pregnant lung transplant patients have a higher risk of neonatal complications. The live-birth rate is the lowest among transplant recipients with rates ranging from 42% to 62% reported 26,54,57 and the preterm birth rate is 58%. 26 A single-center series of pediatric follow up found no evidence of immunocompromise in the children.…”

“…26 A single-center series of pediatric follow up found no evidence of immunocompromise in the children. 57…”