Maternal and perinatal adverse outcomes in women with pre-eclampsia cared for at facility-level in South Africa: a prospective cohort study

Nathan, Hannah L.; Seed, Paul; Hezelgrave, Natasha L.; Greeff, Annemarie de; Lawley, Elodie; Conti‐Ramsden, Frances; Anthony, John; Steyn, Wilhelm; Hall, David; Chappell, Lucy C; Shennan, Andrew

doi:10.7189/jogh.08.020401

Cited by 45 publications

(38 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…LBW was observed 40.7% in pre-eclampsia and 14.9% in other hypertensive disorders by Bonsaffoh [10]. Nathan [7] observed preterm births at<34 weeks in 41.7% and at <37 weeks in 70%. Low birth weight is a major determinant of mortality, morbidity and disability in infancy and childhood as well as long term impact on health outcomes in adulthood [8,9,10] In the present study, still birth and neonatal death rate was 4.5% and 3.5% respectively.…”

Section: Discussion:-mentioning

confidence: 95%

Maternal and Perinatal Outcome in Pregnancies Complicated With Hypertensive Disorder of Pregnancy.

Verma¹,

ijar²

2019

IJAR

View full text Add to dashboard Cite

Background:Hypertensive disorders in pregnancy remain a major global health issue because of the associated perinatal morbidity and mortality. The outcomes of women with hypertensive disorders in pregnancy in our hospital in rural area of India have not yet been documented. Objective: To determine maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy at a tertiary care hospital in rural area of India. Material and methods: A prospective study was undertaken on 200 consecutive women of hypertensive disorder in pregnancies that were managed in the Department of Obstetrics &Gynaecology in our hospital from October 2017 to September 2018. The demographic data, clinical and laboratory findings delivery route, indications of caesarean section, foetal and maternal complications were determined. Results:Out of 200 women, 62.2% were found to have pre-eclampsia, 8% had eclampsia, and 27 % had gestational hypertension and 2.5% had chronic hypertension. Proteinuria was demonstrated in 67.5%, thrombocytopenia in 15.5%, liver dysfunction in 11%, abruptio placenta in 4.5%, HELLP syndrome in 3%, and retinal detachment in 0.5% of women. 46.5% women had caesarean section delivery. There was no maternal mortality. 45% neonates were small for gestational age (SGA), 22.5% needed NICU admission. There were 4.5% still births and 3.5% neonatal deaths. Conclusions:Hypertensive disorder of pregnancy is associated with increased risk of maternal and perinatal adverse outcome. The complications could be reduced by regular antenatal checkup , early identification of hypertension and timely referral and specialist care during labour and after birth.

show abstract

Section: Discussion:-mentioning

confidence: 95%

Maternal and Perinatal Outcome in Pregnancies Complicated With Hypertensive Disorder of Pregnancy.

Verma¹,

ijar²

2019

IJAR

View full text Add to dashboard Cite

show abstract

“…En la Tabla 5 se puede observar que los recién nacidos de madres con preeclampsia tienen mayor riesgo de presentar afecciones, tales como ser prematuros (OR = 9,63), pequeños para la edad gestacional (OR = 3,80), Apgar al primer minuto de vida factores que incrementa la probabilidad de preeclampsia, hay ciertas características propias de la mujer que la predisponen a desarrollar dicha patología, en el presente estudio se evidenció que las mujeres mayores de 35 años tienen mayor predisposición a desarrollar preeclampsia (OR 1,84, IC95 % 1,46-2,31, p < 0,001). Nathan et al (9), en un estudio de madres y perinato asociado a preeclampsia en Sudáfrica, concluye que las mujeres de 30 años a más tenían 3,5 % mayor riesgo de presentar preeclampsia. Bilano et al (10), en un estudio en países en vías de desarrollo con 276 388 madres y sus productos, encontró una asociación importante entre la edad materna mayor a 30 años y el bajo nivel de educación.…”

Section: Discussionunclassified

Resultados maternos y perinatales de preeclampsia en el Hospital Hipólito Unanue de Tacna

Zaga

Rendón

Mamani

2020

RMB

View full text Add to dashboard Cite

La preeclampsia constituye una de las principales causas de mortalidad materna y perinatal. Objetivo: Determinar los resultados maternos y perinatales de la preeclampsia. Material y métodos: Estudio analítico de casos y controles, se incluyó a todas las madres cuyos partos fueron atendidos en el Hospital Hipólito Unanue de Tacna durante los años 2014 a 2018, los datos se obtuvieron del Sistema Informático Perinatal. Se comparó los casos con los controles mediante frecuencias absolutas y relativas. Se utilizó el estadígrafo Chi2, considerando asociación significativa cuando el “p” sea menor de 0,05. Para la determinación de resultados maternos y perinatales adversos se utilizó el Odds Ratio con intervalo de confianza al 95 %, considerando riesgo significativo cuando el intervalo de confianza esté por encima de 1. Resultados: La incidencia de gestantes con preeclampsia fue de 2,8 %. Los resultados maternos asociados a la preeclampsia fueron: desprendimiento prematuro de placenta (OR = 6,41), terminación por cesárea (OR = 43,13) y muerte materna (OR = 11,60). Los resultados perinatales fueron: prematuridad (OR = 9,63), pequeños para la edad gestacional (OR = 3,80), Apgar al primer minuto de 4 a 6 (OR = 2,51), Apgar a los 5 minutos de 0 a 3 (OR = 6,29), hipoglicemia (OR = 2,65) y mortalidad perinatal (OR = 3,94) en comparación con los recién nacidos de madres sin preeclampsia. Conclusiones: La preeclampsia se asocia a mayor morbilidad y mortalidad materna y perinatal.

show abstract

“…Infants born preterm due to preeclampsia are at higher risk of some long-term health issues including learning disorders, cerebral palsy, epilepsy, deafness, and blindness [1,2]. Hypertensive disorders of pregnancy contribute to 14% of all maternal deaths, the majority of which occur in low-and middle-income countries [3].…”

Section: Introductionmentioning

confidence: 99%

Exploring perspectives, preferences and needs of a telemonitoring program for women at high risk for preeclampsia in a tertiary health facility of Karachi: a qualitative study protocol

2020

View full text Add to dashboard Cite

Background In Pakistan, deaths from preeclampsia/eclampsia (PE/E) represent one-third of maternal deaths reported at tertiary care hospitals. To reduce the morbidity and mortality associated with PE/E, an accessible strategy is to support pregnant women at high risk for preeclampsia (HRPE) by closely monitoring their blood pressures at home (i.e., telemonitoring) for the earliest signs of preeclampsia. This could lead to the earliest possible detection of high blood pressure, resulting in early intervention such as through medications, hospitalization, or delivery of the baby. The study aims to explore the perspectives, preferences and needs of telemonitoring (TM) for pregnant women at HRPE in Karachi, to inform future implementation strategies. Methods The study will employ an exploratory qualitative research design. The study will be conducted at the Jinnah Postgraduate Medical Centre (JPMC) hospital and Aga Khan University Hospital (AKUH) in Karachi, Sindh, Pakistan. Data will be collected through key-informant interviews (KIIs) and in-depth patient interviews (IDPIs). IDPIs will be conducted with the pregnant women at HRPE who are visiting the out-patient department/ antenatal clinics of JPMC hospital for antenatal check-ups and immunizations. KIIs will be conducted with the obstetricians, Maternal, neonatal and child health (MNCH) specialists and health care providers at JPMC, as well as TM experts from Karachi. Study data will be analyzed through conventional content analysis. Interviews are anticipated to begin in April 2020 and to be completed during the summer of 2020. Discussion This is the first study to explore the use of TM program for pregnant women at HRPE in a tertiary health facility in Karachi. The research will help explore perceived benefits associated with the use of a TM program alongside potential facilitators and barriers that may help inform the future implementation of a TM program for pregnant women at HRPE in Karachi.

show abstract

Maternal and perinatal adverse outcomes in women with pre-eclampsia cared for at facility-level in South Africa: a prospective cohort study

Cited by 45 publications

References 38 publications

Maternal and Perinatal Outcome in Pregnancies Complicated With Hypertensive Disorder of Pregnancy.

Maternal and Perinatal Outcome in Pregnancies Complicated With Hypertensive Disorder of Pregnancy.

Resultados maternos y perinatales de preeclampsia en el Hospital Hipólito Unanue de Tacna

Exploring perspectives, preferences and needs of a telemonitoring program for women at high risk for preeclampsia in a tertiary health facility of Karachi: a qualitative study protocol

Contact Info

Product

Resources

About