Maternal and perinatal health outcomes by body mass index category

Dodd, Jodie M; Grivell, Rosalie M; Nguyen, Anh–Minh; Chan, Annabelle; Robinson, Jeffrey S.

doi:10.1111/j.1479-828x.2010.01272.x

Cited by 189 publications

(110 citation statements)

References 15 publications

Supporting

Mentioning

107

Contrasting

Unclassified

Order By: Relevance

“…The impact of maternal overweight and obesity during pregnancy and childbirth is substantial, with a large proportion of pregnant women being overweight or obese, and estimates have increased from 35% reported in 2006 [7] to more recent figures in the order of 50% or more [8,9,10,11]. There are well-documented risks of poor health outcomes associated with obesity during pregnancy, and the risks increase as the BMI increases [7,9].…”

Section: Tablementioning

confidence: 99%

“…Complicating the relationship between the maternal prepregnancy BMI and pregnancy outcomes is the independent effect of gestational weight gain (GWG), which is also associated with many of these same adverse pregnancy outcomes [7,9,17,18]. There is a substantial amount of literature on maternal weight gain in pregnancy that has been summarized by the Institute of Medicine [19,20].…”

Section: Tablementioning

confidence: 99%

“…Infants born to women who are overweight or obese are more likely to require nursery admission and treatment for both hypoglycemia and jaundice [7,9]. These infants are also more likely to have a birth weight above 4 kg [9,12,13,14], which in turn has been recognized as a risk factor for subsequent obesity in both childhood and adulthood [15,16]. …”

Section: Tablementioning

confidence: 99%

“…Both maternal overweight and obesity are risk factors for the subsequent development of gestational diabetes [7,9,32]. Metabolically, obesity and gestational diabetes share similar characteristics, including insulin resistance, hyperglycemia, hyperlipidemia, and a low-grade state of chronic inflammation, which in turn has been shown to alter the availability and the placental transfer of nutrients to the developing fetus [31].…”

Section: Tablementioning

confidence: 99%

“…There are well-documented risks of poor health outcomes associated with obesity during pregnancy, and the risks increase as the BMI increases [7,9]. Recognized pregnancy complications include an increased risk of hypertension, preeclampsia, gestational diabetes, and the need for both induction of labor and a caesarean section [7,9,12]. …”

Section: Tablementioning

confidence: 99%

See 4 more Smart Citations

Dietary and Lifestyle Advice for Pregnant Women Who Are Overweight or Obese: The LIMIT Randomized Trial

Dodd¹

2014

Ann Nutr Metab

Self Cite

View full text Add to dashboard Cite

Overweight and obesity during pregnancy are common and are associated with an increased risk of adverse health outcomes for both the mother and the infant. However, robust evidence about the effect of antenatal dietary and lifestyle interventions on health outcomes is lacking. We conducted a multicenter, randomized trial, recruiting 2,212 women (from 3 public maternity hospitals across South Australia) with a singleton pregnancy between 10⁺⁰ and 20⁺⁰ weeks' gestation and a BMI ≥25. The women were randomized to lifestyle advice (n = 1,108) or standard care (n = 1,104). Women randomized to lifestyle advice participated in a comprehensive dietary and lifestyle intervention over the course of their pregnancy (delivered by research staff), while women randomized to standard care received pregnancy care according to local guidelines, which did not include such information. Provision of the lifestyle intervention was associated with a significant 18% relative risk reduction in the chance of infants being born with a birth weight above 4 kg. No other significant differences were identified in maternal pregnancy and birth outcomes between the two treatment groups. Observational studies highlight the association between a high infant birth weight and the subsequent risk of childhood and adulthood obesity. Antenatal interventions that are effective in reducing high infant birth weights therefore represent a significant strategy to tackle obesity from a population health perspective, while ongoing interrogation of the biospecimens and measurements, including ongoing childhood follow-up, will provide a unique opportunity to evaluate the mechanistic pathways of maternal-to-infant/childhood obesity.

show abstract

Section: Tablementioning

confidence: 99%