Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile

Haye, M.; Cartes, G.; Gutierrez, Jorge; Ahumada, Paz; Krause, Bernardo J.; Merialdi, Mario; González, Rogelio

doi:10.1080/14767058.2021.1902498

Cited by 14 publications

(14 citation statements)

References 14 publications

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“…However, these reported studies have yielded conflicting findings leading to contradictory conclusions. Some reports indicate that there are no major adverse outcomes of SARS‐CoV‐2 infection in pregnancy, 4,5 others have reported serious pregnancy complications such as preterm births, neurological disorders, miscarriages, and maternal deaths in women infected with SARS‐COV2 during pregnancy 6‐13 . Multiple systematic reviews have been conducted that have majorly described the risk of vertical transmission and maternal presentation associated with COVID‐19.…”

Section: Introductionmentioning

confidence: 99%

Differential impact of COVID‐19 in pregnant women from high‐income countries and low‐ to middle‐income countries: A systematic review and meta‐analysis

Gajbhiye

Sawant

Kuppusamy

et al. 2021

Intl J Gynecology & Obste

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Background SARS‐CoV‐2 has infected a large number of pregnant women. Objective To compare clinical, perinatal outcomes of women with COVID‐19 from high‐income countries (HICs) and low‐ to middle‐income countries (LMICs). Search strategy Online databases were searched. Selection criteria Original studies on pregnant women with COVID‐19 were included. Data collection and analysis Information on clinical presentation, co‐morbidities, pregnancy outcomes, neonatal outcomes, and SARS‐CoV‐2 infection in neonates was extracted. Main results The pooled estimate of SARS‐CoV‐2 positive neonates is 3.7%. Symptomatic presentations are less common in LMICs compared to HICs (odds ratio [OR] 0.38). Diabetes (OR 0.5), hypertension (OR 0.5), and asthma (OR 0.14) are commonly reported from HICs; hypothyroidism (OR 2.2), anemia (OR 3.2), and co‐infections (OR 6.0) are commonly reported in LMICs. The overall risk of adverse pregnancy outcomes is higher in LMICs compared to HICs (OR 2.4). Abortion (OR 6.2), stillbirths (OR 2.0), and maternal death (OR 7.8) are more common in LMICs. Preterm births and premature rupture of membranes are comparable in both groups. Neonatal deaths (OR 3.7), pneumonia (OR 7.5), and neonatal SARS‐CoV‐2 infection (OR 1.8) are commonly reported in LMICs. Conclusions In LMICs, pregnant women and neonates are more vulnerable to adverse outcomes due to COVID‐19. PROSPERO registration no: CRD42020198743.

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Section: Introductionmentioning

confidence: 99%

Differential impact of COVID‐19 in pregnant women from high‐income countries and low‐ to middle‐income countries: A systematic review and meta‐analysis

Gajbhiye

Sawant

Kuppusamy

et al. 2021

Intl J Gynecology & Obste

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“…Further, only 9.3% required intensive care, with invasive ventilatory support in about 5.0% of them [26]. Studies in Chile and the United States and several countries of the European, American, Asian, and African continents have also classified the majority of pregnant women with COVID-19 as mild and moderate cases of the disease, with low need for intensive care and invasive ventilatory support, as well as low frequency of pulmonary impairment on tomography [2] [17] [27]. Notably, in the studies above, the motivation for hospitalization was labor [17] [21] [27].…”

Section: Discussionmentioning

confidence: 99%

Clinical and Evolutionary Characteristics of Pregnant and Postpartum Women with COVID-19 Admitted to a Hospital in the Central Region of Brazil

Kubiszeski¹,

Carmo²,

Carmo³

et al. 2022

OJOG

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Objective: To describe the demographic and evolutionary characteristics of pregnant and postpartum women with coronavirus disease 2019 (COVID-19) admitted to a medium-sized hospital in Brazil. Method: This is a descriptive and retrospective study, collected from medical records, from March 2020 to October 2021 in a hospital located in Cuiabá (MT). Results: Pregnant and puerperal women with COVID-19 who needed hospitalization were mixedrace, from the metropolitan area, and carriers of moderate and severe forms of the disease. The primary risk condition found was overweight/obesity, and pre-gestational diabetes, hypertension, asthma, and autoimmune disease were the most prevalent comorbidities in the group. Elevated lactate dehydrogenase (LDH), c-reactive protein (CRP), and D-dimer were relevant laboratory findings in this group of patients. The most frequent maternal outcomes were respiratory failure, invasive ventilatory support, thromboembolic phenomena, sepsis, and preterm labor. Maternal death occurred in 6.4% of pregnant women. Most maternal deaths were of women who lived in the interior of the state, and the minority arrived on adequate ventilatory support. Prematurity and the need for neonatal intensive care unit (NICU) were significant complications for neonates. Stillbirth/neonatal mortality occurred in 11.0%. Conclusion: The clinical conditions at hospitalization were associated with worse living conditions and lack of access to health care, resulting in increased chances of severity and worsening outcomes in this group of women and neonates.

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“…48 Şili'de gerçekleştirilen bir başka araştırmada da düşük doğum ağırlıklı doğumların oranının enfekte kadınlarda ülke ortalaması olan %6'dan daha yüksek bir oranda %17 düzeyinde görüldüğü bildirilmiştir. 49 Düşük doğum ağırlığının yetişkin dönemde kardiyovasküler mortaliteyi arttırdığı; hipertansiyon, diyabet, metabolik sendrom ve akciğer hastalıklarına eğilime yol açtığı bilinmektedir. 50 SARS ile enfekte olmuş gebelerde abortus sıklığının arttığı bildirilmişti.…”

Section: Gebeliğin Seyri Ve Obstetrikkomplikasyonlarunclassified

Inflammatory Response to COVID-19 Infection During Pregnancy and Obstetrical Complications

TİMUR¹,

Bayram²,

ÖZGÖZEN³

et al. 2021

TJRMS

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Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile

Cited by 14 publications

References 14 publications

Differential impact of COVID‐19 in pregnant women from high‐income countries and low‐ to middle‐income countries: A systematic review and meta‐analysis

Differential impact of COVID‐19 in pregnant women from high‐income countries and low‐ to middle‐income countries: A systematic review and meta‐analysis

Clinical and Evolutionary Characteristics of Pregnant and Postpartum Women with COVID-19 Admitted to a Hospital in the Central Region of Brazil

Inflammatory Response to COVID-19 Infection During Pregnancy and Obstetrical Complications

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