Maternal and perinatal outcomes in pregnant women with SARS-CoV-2 infection: a retrospective observational study

Abstract

Objectives The aim of our study is to present the impact on maternal and perinatal outcomes of the COVID pandemic in our patients. Methods We retrospectively reviewed the medical records of all pregnant women from March to December 2020 in Infanta Leonor Universitary Hospital, in Madrid. Infected women during the 3rd trimester of pregnancy or at delivery time with SARS-CoV2 diagnosis composed infected group, and non-infected women with SARS-CoV2 composed non-infected group. The infection status was determined via RT-PCR of nasopharyngeal swab specimen. Results 1262 non-infected pregnant women and 86 SARS-CoV2 positive pregnant women were admitted to our clinic during the study period. Within the group of infected pregnant women, they were 49 cases (56.98%) symptomatic and 37 cases (43.02%) asymptomatic. In the group of symptomatic infected women, the majority were mild cases (80.23%). In the group of uninfected pregnant women, the main complication was gestational diabetes 14 (1.09%) We did not find any complications during pregnancy in case group. Cesarean section was performed in 16.67% of the infected pregnant women and in 21.71% of the control group. Mean neonatal birth weight was 3.240 g in case group and 3.210 g in non-infected group. Neonatal admission to NICU was 9.52% in cases while in the control group was 1.19%. Conclusion Infection does not worsen the prognosis of pregnancy in terms of low birth weight of the newborn, but is associated with a greater increase in neonatal admission in NICU.