‘Maternal antecedents to cerebral palsy in preterm infants’

Walstab, Janet E.; Bell, Robin J.; Reddihough, Dinah; Brennecke, Shaun; Bessell, Christine; Beischer, Norman A.

doi:10.1111/j.1469-8749.2002.tb00313.x

Cited by 2 publications

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Übergewicht und Adipositas vor der Schwangerschaft sind mit antenatalen und peripartalen Komplikationen wie Gestationsdiabetes, Präeklampsie, schwangerschaftsinduzierter Hypertonie und Komplikationen unter der Geburt assoziiert 41 , 42 . Des Weiteren scheint die mütterliche Adipositas zusätzlich negative Auswirkungen auf das Neugeborene 43 , wie beispielsweise kognitive Defizite 44 , 45 , autistische Entwicklungsstörungen 46 , 47 oder Zerebralparese (CP) 48 , 49 , 50 , 51 , 52 , zu haben.…”

Section: Neurologische Und Kognitive Entwicklungunclassified

Maternal Overweight, Inflammation and Neurological Consequences for the Preterm Child: Results of the ELGAN Study

Brodowski

Büter

Kohls

et al. 2019

Geburtshilfe Frauenheilkd

View full text Add to dashboard Cite

Maternal overweight and obesity are prenatal risk factors for obstetrical complications, preterm birth, neonatal morbidity as well as cognitive and behavioural developmental disorders in children. Paediatric morbidity and mortality as well as child development disorders are significantly associated with maternal obesity. Particularly in the neurodevelopmental and psychiatric area, it is becoming increasingly clear that, in children of mothers with an increased body mass index (BMI), there is a high correlation with childhood cognitive disabilities, attention disorders, and diseases on the autistic spectrum. The ELGAN (Extremely Low Gestational Age Newborn) study is a multicentre study which has been supported since 2000 by the National Institutes of Health (NIH) and whose objective is to research predictors for neonatal brain damage and neurological-cognitive sequelae in premature infants. The areas of focus are the connection between maternal overweight and obesity and pregnancy complications, APGAR scores and systemic inflammatory markers. In this overview, our aim is to summarise the work in this area and discuss it critically on the basis of current literature. We will examine the hypothesis whether maternal overweight and obesity in terms of a chronic inflammatory state is associated with neonatal inflammation which in turn is associated with an unfavourable development prognosis.

show abstract

Section: Neurologische Und Kognitive Entwicklungunclassified

Maternal Overweight, Inflammation and Neurological Consequences for the Preterm Child: Results of the ELGAN Study

Brodowski

Büter

Kohls

et al. 2019

Geburtshilfe Frauenheilkd

View full text Add to dashboard Cite

show abstract

Maternal Infection and Risk of Cerebral Palsy in Term and Preterm Infants

et al. 2004

View full text Add to dashboard Cite

We tested the hypothesis that term and preterm infants exposed to maternal infection at the time of delivery are at increased risk of developing cerebral palsy (CP). STUDY DESIGN:A population-based case-control study was conducted using Washington State birth certificate data linked to hospital discharge data. Cases (688) were children r6 years old, singleton births, hospitalized during 1987 to 1999 with an ICD-9 diagnosis code for CP. Controls were 3068 singleton birth infants randomly selected from birth records for the same years without CP-related hospitalizations. Infection information was available only for the birth hospitalization. RESULTS:Infants of women who had any infection during their hospitalization for delivery were at increased risk of CP (odds ratio (OR) 3.1, 95% confidence interval (CI) 2.3 to 4.2). This was observed for term deliveries (OR 1.8, 95% CI 1.1 to 2.8) and preterm deliveries (OR 2.3, 95% CI 1.3 to 4.2). CONCLUSIONS:Our results suggest that maternal infection is a risk factor for CP in both term and preterm infants.

show abstract

‘Maternal antecedents to cerebral palsy in preterm infants’

Cited by 2 publications

References 1 publication

Maternal Overweight, Inflammation and Neurological Consequences for the Preterm Child: Results of the ELGAN Study

Maternal Overweight, Inflammation and Neurological Consequences for the Preterm Child: Results of the ELGAN Study

Maternal Infection and Risk of Cerebral Palsy in Term and Preterm Infants

Contact Info

Product

Resources

About