Maternal exposure to housing renovation during the periconceptional period and the risk of offspring with isolated congenital heart disease: a case-control study

Qu, Pengfei; Zhao, Doudou; Yan, Mingxin; Liu, Danmeng; Zhang, Ruo; Li, Shanshan; Pei, Leilei; Yan, Hong; Zeng, Lingxia; Dang, Shaonong

doi:10.1186/s12940-023-00990-z

Cited by 4 publications

(1 citation statement)

References 33 publications

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“…Neighborhoods with exposure to environmental pollutants are known to contribute to maternal morbidities such as preeclampsia and placental abruption, which in turn can raise the risk of maternal mortality ( 208 , 209 ). Exposure to housing renovation during the periconceptional period increases the risk of Congenital Heart Disease (adjusted OR: 1.77, 95% CI: 1.34, 2.33) ( 210 ).…”

Section: Part II Effect Of Racial and Social Determinants Of Health O...mentioning

confidence: 99%

Impact of sex, race, and social determinants of health on neonatal outcomes

Alur,

Holla,

Hussain

2024

Front. Pediatr.

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Despite the global improvements in neonatal outcomes, mortality and morbidity rates among preterm infants are still unacceptably high. Therefore, it is crucial to thoroughly analyze the factors that affect these outcomes, including sex, race, and social determinants of health. By comprehending the influence of these factors, we can work towards reducing their impact and enhancing the quality of neonatal care. This review will summarize the available evidence on sex differences, racial differences, and social determinants of health related to neonates. This review will discuss sex differences in neonatal outcomes in part I and racial differences with social determinants of health in part II. Research has shown that sex differences begin to manifest in the early part of the pregnancy. Hence, we will explore this topic under two main categories: (1) Antenatal and (2) Postnatal sex differences. We will also discuss long-term outcome differences wherever the evidence is available. Multiple factors determine health outcomes during pregnancy and the newborn period. Apart from the genetic, biological, and sex-based differences that influence fetal and neonatal outcomes, racial and social factors influence the health and well-being of developing humans. Race categorizes humans based on shared physical or social qualities into groups generally considered distinct within a given society. Social determinants of health (SDOH) are the non-medical factors that influence health outcomes. These factors can include a person&apos;s living conditions, access to healthy food, education, employment status, income level, and social support. Understanding these factors is essential in developing strategies to improve overall health outcomes in communities.

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Section: Part II Effect Of Racial and Social Determinants Of Health O...mentioning

confidence: 99%

Impact of sex, race, and social determinants of health on neonatal outcomes

Alur,

Holla,

Hussain

2024

Front. Pediatr.

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Effects of Long‐Term Exposure to Ambient Formaldehyde on Hypertension and Angina Pectoris Symptoms: Evidence From the WHO SAGE Cohort Study

Xu,

Shi,

et al. 2024

JAHA

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Background We aimed to investigate the associations of long‐term exposure to ambient formaldehyde with hypertension and angina pectoris symptoms in Chinese adults. Methods and Results Participants' information was obtained from the WHO SAGE (World Health Organization Study on Global Aging and Adult Health) study. The Cox proportional hazards regression model was applied to estimate the associations of formaldehyde with hypertension and angina pectoris symptoms. Mediating effect analysis was used to investigate the mediating effect of hypertension between formaldehyde exposure and angina pectoris symptoms. Long‐term exposure to formaldehyde was positively associated with the risk of angina pectoris symptoms (hazard ratio [HR], 1.66 [95% CI, 1.29–2.13], per interquartile range [IQR], 3.33, 10 15 molecules/cm 2 ) and hypertension (HR, 1.17 [95% CI, 1.02–1.34], per IQR, 3.34, 10 15 molecules/cm 2 ). The associations between formaldehyde and angina pectoris symptoms were greater in participants aged ≥65 years (HR, 1.90 [95% CI, 1.29–2.80]) and in rural areas (HR, 2.71 [95% CI, 1.54–4.77]), whereas the associations of formaldehyde with hypertension were stronger in men (HR, 1.27 [95% CI, 1.02–1.58]), rural areas (HR, 1.22 [95% CI, 0.94–1.59]), and in ever smokers (HR, 1.33 [95% CI, 1.02–1.72]). The mediation effect analysis indicated that 18.44% (95% CI, 2.17–37.65) of the association between formaldehyde exposure and angina pectoris symptoms was mediated by hypertension. Conclusions Long‐term exposure to ambient formaldehyde was positively associated with hypertension and angina pectoris symptoms. The effects of formaldehyde may be modified by age, sex, urbanicity, and smoking status. Hypertension might play a mediating effect in formaldehyde‐induced angina pectoris symptoms.

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Maternal multivitamin supplementation mitigates the risk of fetal congenital heart disease associated with high indoor total volatile organic compounds exposure in east china: a case-control study

Ruan,

Shang,

et al. 2024

Environ Health

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Maternal exposure to housing renovation during the periconceptional period and the risk of offspring with isolated congenital heart disease: a case-control study

Cited by 4 publications

References 33 publications

Impact of sex, race, and social determinants of health on neonatal outcomes

Impact of sex, race, and social determinants of health on neonatal outcomes

Effects of Long‐Term Exposure to Ambient Formaldehyde on Hypertension and Angina Pectoris Symptoms: Evidence From the WHO SAGE Cohort Study

Maternal multivitamin supplementation mitigates the risk of fetal congenital heart disease associated with high indoor total volatile organic compounds exposure in east china: a case-control study

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