2010
DOI: 10.1289/ehp.0901509
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Maternal Exposure to Nitrogen Dioxide during Pregnancy and Offspring Birth Weight: Comparison of Two Exposure Models

Abstract: BackgroundStudies of the effects of air pollutants on birth weight often assess exposure with networks of permanent air quality monitoring stations (AQMSs), which have a poor spatial resolution.ObjectiveWe aimed to compare the exposure model based on the nearest AQMS and a temporally adjusted geostatistical (TAG) model with a finer spatial resolution, for use in pregnancy studies.MethodsThe AQMS and TAG exposure models were implemented in two areas surrounding medium-size cities in which 776 pregnant women wer… Show more

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Cited by 27 publications
(16 citation statements)
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“…Much like particulate matters, ambient SO 2 concentration was associated with mortality [ 29 ], lung cancer [ 30 ], respiratory diseases [ 31 , 32 ] and stillbirth [ 33 ]. Further, the ambient NO 2 concentrations were associated with pulmonary defects [ 34 , 35 ], cardiovascular complications [ 36 ], mortality [ 37 ] and offspring’s birth weight [ 38 ].…”
Section: Discussionmentioning
confidence: 99%
“…Much like particulate matters, ambient SO 2 concentration was associated with mortality [ 29 ], lung cancer [ 30 ], respiratory diseases [ 31 , 32 ] and stillbirth [ 33 ]. Further, the ambient NO 2 concentrations were associated with pulmonary defects [ 34 , 35 ], cardiovascular complications [ 36 ], mortality [ 37 ] and offspring’s birth weight [ 38 ].…”
Section: Discussionmentioning
confidence: 99%
“…However, these methods have some uncertainties [46], and still require some monitor-based data for inputs and model evaluation [24,47]. Several papers compared effect estimates based on alternative exposure methods [3,[17][18][19], but none of them compared effects of PM 2.5 chemical constituents. In the future, we could compare effect estimates of chemical constituents based on alternative exposure methods.…”
Section: Discussionmentioning
confidence: 99%
“…These methods were applied in many studies to estimate exposure based on residence (e.g. mother's actual address or residential county at birth) [17][18][19][20][21]. Applying large buffers (or spatial units) can introduce exposure misclassification due to spatial heterogeneity of pollution [22].…”
Section: Introductionmentioning
confidence: 99%
“…For the ICAPPO analysis, the centers reanalyzed existing data sets that had been created to evaluate the impacts of maternal exposure to air pollution on pregnancy outcomes. The centers relied on outcome data available from routinely collected administrative records (birth certificates) or data collected for a specific study (Bell et al 2007, 2008; Brauer et al 2008; Darrow et al 2011; Gehring et al 2011; Glinianaia et al 2008; Gouveia et al 2004; Ha et al 2004; Jalaludin et al 2007; Lepeule et al 2010; Mannes et al 2005; Morello-Frosch et al 2010; Pesatori et al 2008; Rich et al 2009; Slama et al 2009; van den Hooven et al 2009). More detailed description of the ICAPPO centers has been previously published (Parker et al 2011; Woodruff et al 2010).…”
Section: Methodsmentioning
confidence: 99%