Maternal luteoma of pregnancy: A rare case report

Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review

“…Several authors have shown virilization symptoms in the female fetus [11], a finding that was absent in our case report. It is hypothesized that despite the maternal hyperandrogenemia produced by the pregnancy luteoma between the critical 9-14 weeks of 3 Case Reports in Obstetrics and Gynecology 6 Case Reports in Obstetrics and Gynecology 7 Case Reports in Obstetrics and Gynecology development, the placenta is somewhat protective against the masculinization of the female fetus by converting the excess androgens to estrogens [5]. Emerging evidence has implicated androgenemia, specifically elevated testosterone, as a causative for preeclampsia [28].…”

Antenatal diagnosis and management of pregnancy luteoma: A case report and literature review

“…However, it was also noted that pregnancy [2] 1. US+T [3] US+T HA US follow-up, bilateral ovarian lesions resection at the cesarean/Y Female infant with complete masculinization Wang et al [4] US+MRI N US and MRI follow-up, bilateral ovarian lesions resection at the cesarean/Y Normal appearance female infant Wang et al [5] US+MRI+T HA Vaginal delivery/N Female infant with clitoral hypertrophy Banerjee et al [6] N ART Left ovarian lesions resection at the cesarean/Y Normal appearance male infant Spitzer et al [7] US+MRI+T ART+HA+HD-CP+IUGR Laparotomy and right salpingo-ophorectomy with omentectomy postpartum/Y Virilized female infant Dahl et al [8] US+MRI+T HA+HDCP Cesarean, cystic-appearing ovaries untreated/N Normal appearance male infant Tan et al [9] US ART Laparotomy and right salpingo-oophorectomy/Y Norma appearance male infant Wang et al [10] US+T ART+HA Not mentioned/Y Normal appearance male infant Ugaki et al [11] US N US follow up, left ovarian lesions resection at the cesarean/Y Virilized female infant Tannus et al [12] US+MRI+T HA Laparotomy and right ovarian lesions resection at 22 wk/Y Normal appearance male infant Masarie et al [13] US+MRI+T HA Laparotomy, cesarean, and right oophorectomy at 37 wk/Y Normal appearance female infant Dasari et al [14] US+T HA Laparotomy and ovarian biopsy at 8 wk/Y Miscarried at 17 wk Nanda et al [15] N N Bilateral partial oophorectomy at the cesarean/Y Normal appearance female infant Ranjan et al [16] US N Left salpingo-oophorectomy at the cesarean/Y Normal appearance infant Wadzinski et al [17] US+MRI ART+HA+HDCP Caesarean section but ovarian lesions not mentioned/N Twin female infants with virilization Limaiem et al [18] US N Laparotomy and left salpingo-oophorectomy/Y Not mentioned Rapisarda et al [19] US+T HA US follow up, laparotomy, cesarean and right oophorectomy at 34 wk/Y Normal appearance male infant Verma et al [20] N N Right oophorectomy at the cesarean/Y Normal appearance female infant Brar et al [21] US N Laparotomy and left ovarian lesions resection/Y N(ectopic pregnancy) Khurana and O'Boyle [22] US+MRI N Laparotomy and mass resection at 23 wk/Y Full term birth and normal-looking infant Rathore et al [23] US N Laparotomy and salpingo-oophorectomy/Y N(ectopic pregnancy) Smolarczyk et al [24] T HA Resection of the right ovary and partial resection of the left ovary/Y Normal appearance female infant Mvunta et al…”

“…The factors of morbidity, pathogenesis, and their potential influences on pregnancy remain unclear. Using the search terms “pregnancy luteoma,” we conducted a comprehensive literature review from 2000 to the present on PubMed and Web of Science databases, resulting in the identification of 25 reports encompassing 26 cases of pregnancy luteomas [2–26] (Table 1). To summarize the literature, it is noteworthy that achieving an accurate prenatal diagnosis poses a significant challenge.…”

“…[2,7,12–14,18,19,22,23] In addition, partial ovariectomy or oophorectomy remained the commonly performed procedures, in these instances, the biopsy ought to have sufficed and preservation of the ovaries should have been prioritized. [2–4,6–10,12–22,24,25] In the present study, we present a complete case of pregnancy luteoma including antenatal diagnosis and management strategy. Written consent was obtained from all patients.…”

“…To summarize the literature, it is noteworthy that achieving an accurate prenatal diagnosis poses a significant challenge. Some reports have described luteoma detection occurring incidentally during routine ultrasonography antepartum, [2][3][4][5]7,9,[12][13][14]16,18,19,[21][22][23] in such cases, when the ultrasound and magnetic resonance imaging (MRI) results suggested a diagnosis of ovarian neoplasia, a laparotomy was offered in order to rule out malignancy. [2,7,[12][13][14]18,19,22,23] In addition, partial ovariectomy or oophorectomy remained the commonly performed procedures, in these instances, the biopsy ought to have sufficed and preservation of the ovaries should have been prioritized.…”