Maternal Physiology of Pregnancy

Longo, Lawrence D.

doi:10.1007/978-1-4939-7483-2_10

Cited by 2 publications

(3 citation statements)

References 294 publications

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Section: Introductionmentioning

confidence: 99%

“…In pregnancy, women undergo various physiological changes, which increases their risk of venous thromboembolic events (VTE) 1 . Increases in serum levels of oestrogen and progesterone 1,2 as well as the enlarging uterus 3 increase venous dilation and stasis reducing venous return 4 . More importantly, the concentrations of key clotting factors increase, whereas thrombosis and fibrinolysis inhibiting proteins decrease 5 .…”

Section: Introductionmentioning

confidence: 99%

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Venous thromboembolism prophylaxis in pregnancy: Are we adequately identifying and managing risks?

Choy

Emmett

Wong

2022

Aust NZ J Obst Gynaeco

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Pregnancy is a well‐known risk factor of venous thromboembolism. We retrospectively reviewed case histories of 82 pregnant women who developed symptoms of venous pathology, thrombophlebitis, deep vein thrombosis (DVT) or pulmonary embolus (PE) while receiving care at our hospital. We found the VTE risk identification and documentation during their pregnancies were deficient resulting in the omission of appropriate thromboprophylaxis. Many confirmed VTE cases (antenatally or postpartum) were not on thromboprophylaxis prior to diagnosis despite having multiple risk factors. We recommend the use of a risk assessment tool by clinicians for accurate risk identification ensuring proper risk management at different stages of pregnancy.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Venous thromboembolism prophylaxis in pregnancy: Are we adequately identifying and managing risks?

Choy

Emmett

Wong

2022

Aust NZ J Obst Gynaeco

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“…During each trimester, there is a physiological modification of the maternal body to accommodate the developing fetus (Saleem et al, 2022). Pregnancy is considered an anabolic and catabolic phase requiring several metabolic adjustments to sustain the growth and developmental demands of the fetus while maintaining maternal homeostasis (King, 2000;Longo, 2018). Normal pregnancy may be characterized by both physiologic and pathologic changes (Mba et al, 2019).…”

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confidence: 99%

Effect of Pregnancy on Hematological Profile of Female Subjects from a Private Hospital in Benin City, Edo State, Nigeria

Ekhegbesela,

Ekhator,

Emina

2024

jasem

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Pregnancy is characterized by important variations in virtually every organ system to accommodate the growing and developing fetoplacental entity. Hence, the objective of this study is to assess the effect of pregnancy on hematological profile of female subjects attending a private hospital in Benin City, Edo State, Nigeria using eighty female volunteered individuals comprising sixty pregnant subjects and twenty nonpregnant subjects. The pregnant group was further categorized into three trimesters, each consisting of twenty participants. Results were presented as Mean ± SD and analyzed using GraphPad Prism 5 software (GraphPad Software Inc.), and p < 0.05 was considered statistically significant. Overall, the mean values of lymphocytes, red blood cells, hematocrit, hemoglobin, and platelets were decreased in the pregnant cohort when compared to the nonpregnant cohort, whereas an incremental rise in white blood cell, and granulocytes were observed in the pregnant cohort when compared to the nonpregnant cohort. A statistically significant difference (p < 0.05) in the mean hematocrit and hemoglobin values was observed when comparing the first-trimester participants with the control participants, although white blood cells, granulocytes, lymphocytes, red blood cells, and platelets were not different (p > 0.05). The average values for white blood cells, granulocytes, red blood cells, hematocrit, and hemoglobin between second-trimester individuals and those of nonpregnant individuals exhibited a significant variance (p < 0.05), while the average lymphocyte and platelet counts showed no significance (p > 0.05). the mean white blood cells, granulocytes, lymphocytes, red blood cells, hematocrit, hemoglobin, and platelet counts for the third-trimester subjects were significantly different (p < 0.05) when compared to the control subjects. The study outcome suggests that pregnancy affects hematological indices and may be a risk predictor for pregnancy-associated complications.

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Maternal Physiology of Pregnancy

Cited by 2 publications

References 294 publications

Venous thromboembolism prophylaxis in pregnancy: Are we adequately identifying and managing risks?

Venous thromboembolism prophylaxis in pregnancy: Are we adequately identifying and managing risks?

Effect of Pregnancy on Hematological Profile of Female Subjects from a Private Hospital in Benin City, Edo State, Nigeria

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