Maternal pre‐pregnancy body mass index, gestational weight gain, and pubertal timing in daughters: A systematic review and meta‐analysis of cohort studies

Abstract

The timing of daughter's puberty onset is constantly earlier. It is still unclear about the maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) as important prenatal factors that may affect offspring's onset of puberty.Thus, we evaluated the association among maternal pre-pregnancy BMI, GWG, and daughters' early pubertal development based on the existing literature. Literature review was conducted in different databases, including Web of Science, Pubmed, Wiley, ScienceDirect, Web of Science, and Chinese National Knowledge Infrastructure databases up to June 2021. We selected random effects model or fixed effects model for meta-analysis according to the I 2 statistics value to obtain the summary measurement. A total of 12 cohort studies were included. Compared to maternal pre-pregnancy normal weight, maternal pre-pregnancy overall overweight/obesity

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Obstructive and restrictive spirometry from school age to adulthood: three birth cohort studies

“…Previous analysis in one of our birth cohorts (ALSPAC) suggested that catch-up growth is possible around puberty and is associated with later onset and higher velocity of pubertal growth. 40 Given the relationships between the early-onset of puberty with child’s and maternal obesity and gestational weight gain, 41 it has been suggested that a combination of interventions to reduce childhood obesity and obesity in pregnancy may have substantial impact on life-long health. 42 …”

Lung function trajectories from school age to adulthood and their relationship with markers of cardiovascular disease risk

“… 41 However, we have previously shown in ALSPAC that catch-up growth in FEV 1 and FVC is possible around puberty, and that later onset and higher velocity of pubertal growth are associated with higher maximally attained lung function at age 24 years. 42 Given the global trends towards earlier puberty 43 and a significant relationship between the early onset of puberty with child’s obesity 44 and maternal obesity and gestational weight gain, 45 a combination of intervention tackling childhood obesity to protect current generations, and obesity in pregnancy to protect future generations (particularly among women with impaired lung function), 41 may have substantial impact on overall health. This should be coupled with measures to minimise exposure to tobacco smoke, air pollution and other adverse environmental exposures.…”