Maternal pre-pregnancy risk factors for miscarriage from a prevention perspective: a cohort study in China

The impact of maternal lifestyle factors on periconception outcomes: a systematic review of observational studies

“…The characteristics of the included studies are shown in TABLE 1. Thirty-five studies were identified as prospective (Laurent et al, 1992;Florack et al, 1994;Windham et al, 1997;Caan and C. P. Quesenberry, 1998;Hakim et al, 1998;Jensen et al, 1998;Hull et al, 2000;Kesmodel et al, 2002;Arakawa et al, 2006;Law et al, 2007;Strandberg-Larsen et al, 2008;Bakker et al, 2010;Mook-Kanamori et al, 2010;Prabhu et al, 2010;Wise et al, 2010;Hatch et al, 2012;Mutsaerts et al, 2012;Wise et al, 2012;Bouwland-Both et al, 2013;van Uitert et al, 2013b;Wise et al, 2013, Gaskins et al, 2014bHahn et al, 2014;Radin et al, 2014;Van Uitert et al, 2014;Andersen et al, 2015;Hahn et al, 2015;Cueto et al, 2016;Gaskins et al, 2016;McKinnon et al, 2016;Sapra et al, 2016;Wesselink et al, 2016;Zhou et al, 2016;Parisi et al, 2017), six as retrospective cohort studies (Bolúmar et al, 1997, Axmon et al, 2000, Juhl et al, 2001, Juhl et al, 2003, Axmon et al, 20...…”

“…It is thought that insulin resistance may be involved in several mechanisms, such as diminished endometrial production of adhesion factors and a lower serum lconcentration of immunosuppressive proteins (Veleva et al, 2008). In this review, heterogeneous results for miscarriage in the four included studies were found (Parazzini et al, 1991;Hahn et al, 2014;Xu et al, 2014;Zhou et al, 2016). This can partly be explained by the fact that it is not always clear whether pre-pregnancy or present BMI was used.…”

“…Fourteen studies evaluated the association between maternal lifestyle factors and first trimester miscarriage (Parazzini et al, 1991;Windham et al, 1997;Cnattingius et al, 2000;Kesmodel et al, 2002;Ronnenberg et al, 2002;Strandberg-Larsen et al, 2008;Feodor Nilsson et al, 2014;Gaskins et al, 2014b;Hahn et al, 2014;Xu et al, 2014;Andersen et al, 2015;Hahn et al, 2015;Gaskins et al, 2016;Zhou et al, 2016) (TABLE 4). The impact of smoking was evaluated in three studies (Parazzini et al, 1991;Cnattingius et al, 2000;Xu et al, 2014) all showing a statistically significant increase in risk of miscarriage in smokers.…”

“…The association between BMI, physical activity and miscarriage was evaluated in five studies (Parazzini et al, 1991;Feodor Nilsson et al, 2014;Hahn et al, 2014, Xu et al, 2014Zhou et al, 2016). Higher BMI was shown to significantly increase the risk of miscarriage in two studies (Hahn et al, 2014;Zhou et al, 2016), whereas two other studies showed that moderate physical activity significantly decreased the risk of miscarriage (Feodor Nilsson et al, 2014;Xu et al, 2014).…”

“…This can partly be explained by the fact that it is not always clear whether pre-pregnancy or present BMI was used. Furthermore, only one paper obtained direct measurements of weight and height instead of obtaining this information through self-reported questionnaires (Zhou et al, 2016).…”