Maternal Symptoms of Anxiety During Pregnancy Affect Infant Neuromotor Development: The Generation R Study

Batenburg-Eddes, Tamara van; Groot, Laila de; Huizink, Anja C.; Steegers, Eric A.P.; Hofman, Albert; Jaddoe, Vincent W. V.; Verhulst, Frank C.; Tiemeier, Henning

doi:10.1080/87565640902964508

Cited by 48 publications

(35 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anxiety and depressive disorders are the most prominent disorders in females during reproductive age (Kessler et al, 2012;Wittchen et al, 2011) and their occurrences prior to (Martini et al, 2010;Petzoldt et al, 2014), during (Alder et al, 2007;Chen et al, 2010;Field et al, 2010;Grigoriadis et al, 2013;van Batenburg-Eddes et al, 2009) and after (Glasheen et al, 2010;Murray and Cooper, 1996;Wan and Green, 2009 ) pregnancy are associated with adverse consequences for mother and offspring (e.g. preterm delivery, maternal postpartum depression, excessive infant crying, bonding problems, and adverse child development).…”

Section: Introductionmentioning

confidence: 99%

Risk factors and course patterns of anxiety and depressive disorders during pregnancy and after delivery: A prospective-longitudinal study

Martini

Petzoldt

Einsle

et al. 2015

Journal of Affective Disorders

286

223

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Risk factors and course patterns of anxiety and depressive disorders during pregnancy and after delivery: A prospective-longitudinal study

Martini

Petzoldt

Einsle

et al. 2015

Journal of Affective Disorders

286

223

View full text Add to dashboard Cite

“…Other observations, such as following movements, were scored as present, absent, or excessive. A full description of the measured items has been published (20). An age-appropriate response was labeled "optimal."…”

Section: Methodsmentioning

confidence: 99%

Fetal Programming of Infant Neuromotor Development: The Generation R Study

et al. 2010

Self Cite

View full text Add to dashboard Cite

ABSTRACT:The objective of the study was to examine whether infant neuromotor development is determined by fetal size and body symmetry in the general population. This study was embedded within the Generation R Study, a population-based cohort in Rotterdam. In 2965 fetuses, growth parameters were measured in mid-pregnancy and late pregnancy. After birth, at age 9 to 15 wks, neuromotor development was assessed with an adapted version of Touwen's Neurodevelopmental Examination. Less optimal neuromotor development was defined as a score in the highest tertile. We found that higher fetal weight was beneficial to infant neurodevelopment. A fetus with a 1-SD score higher weight in mid-pregnancy had an 11% lower risk of less optimal neuromotor development (OR: 0.89; 95% CI: 0.82-0.97). Similarly, a fetus with a 1-SD score larger abdominal-to-head circumference (AC/HC) ratio had a 13% lower risk of less optimal neuromotor development (OR: 0.87; 95% CI: 0.79 -0.96). These associations were also present in late pregnancy. Our findings show that fetal size and body symmetry in pregnancy are associated with infant neuromotor development. These results suggest that differences in infant neuromotor development, a marker of behavioral and cognitive problems, are at least partly caused by processes occurring early in fetal life. (Pediatr Res 67: 132-137, 2010)

show abstract

“…At the age of 3 months, home visits were performed to assess neuromotor development using an adapted version of Touwen's Neurodevelopmental examination [183][184][185]. Information about growth (length (height), weight, head circumference) is collected at each visit to the routine child health centres in the study area using standardized procedures.…”

Section: Physical Examinationsmentioning

confidence: 99%

The Generation R Study: design and cohort update 2012

et al. 2012

Self Cite

View full text Add to dashboard Cite

The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. The study is designed to identify early environmental and genetic causes of normal and abnormal growth, development and health during fetal life, childhood and adulthood. The study focuses on four primary areas of research: (1) growth and physical development; (2) behavioural and cognitive development; (3) diseases in childhood; and (4) health and healthcare for pregnant women and children. In total, 9,778 mothers with a delivery date from April 2002 until January 2006 were enrolled in the study. General follow-up rates until the age of 4 years exceed 75%. Data collection in mothers, fathers and preschool children included questionnaires, detailed physical and ultrasound examinations, behavioural observations, and biological samples. A genome wide association screen is available in the participating children. Regular detailed hands on assessment are performed from the age of 5 years onwards. Eventually, results forthcoming from the Generation R Study have to contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.

show abstract

Maternal Symptoms of Anxiety During Pregnancy Affect Infant Neuromotor Development: The Generation R Study

Cited by 48 publications

References 63 publications

Risk factors and course patterns of anxiety and depressive disorders during pregnancy and after delivery: A prospective-longitudinal study

Risk factors and course patterns of anxiety and depressive disorders during pregnancy and after delivery: A prospective-longitudinal study

Fetal Programming of Infant Neuromotor Development: The Generation R Study

The Generation R Study: design and cohort update 2012

Contact Info

Product

Resources

About