Breastfeeding has benefits for mother and important determinant for infant normal growth and development. This study identified and recommends evidence-based practice intervention aimed at overcoming BF constrain to increase continuation among mothers and to identify the factors that help to develop successful breastfeeding promotion strategies. Aims: This review of article aims is to review existing literature to identify the main obstacles for breastfeeding among mothers to their infants. Method: A search of Pro Quest, MEDLINE, CINAHL, MEDLINEINDEX, Clinically KEY, EBSCO, and Google Scholar was conducted to retrieve studies from January 2010 to December 2017. Using inclusion criteria, we selected both qualitative and quantitative studies that described barriers to breastfeeding. Key words used were Breastfeeding mothers; exclusive breastfeeding; infant breastfeeding; maternal barriers of breastfeeding; challenges, obstacles or problems of breastfeeding. Results: Fifteen articles were included in this review six studies addressing maternal barriers for BF, five studies addressing obstacles for appropriate EBF duration and four studies addressing factors associated with early breastfeeding cessation. Result from the studies reviewed identified 30 constraints or barriers, which may lead to discontinue breastfeeding for infant. The literature is rich in documentation stating that continuation of BF is associated with many obstacles.