Engineering research is bases on experiments that give answers how different influential process factors can impact an outcome. Therefore, the research plot has to be designed in order to capture a valid analysis of the results. Many research project use research methodologies as a help to reach the answers in a technical point of view and to determinate the laws of the controlled input variables on the experimental outcome. This paper will show a realistic usage of the response surface methodology with an CCD experimental plan for 2 influence factors on a welding example using FCAW welding process in order to investigate the hydrogen input and the critical implant stress upon changing the heat input and preheat temperature and to define the weldability of API 5L X80 steel welds