2020
DOI: 10.1007/s00249-020-01439-8
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Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats

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Cited by 7 publications
(10 citation statements)
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“…The applied model is based on a recently defined cardiomyocyte model [ 11 ]. It involves time-dependent and independent ionic currents, and the related parameters were optimized by voltage-clamp experiments using adult rat ventricular cells.…”
Section: Methodsmentioning
confidence: 99%
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“…The applied model is based on a recently defined cardiomyocyte model [ 11 ]. It involves time-dependent and independent ionic currents, and the related parameters were optimized by voltage-clamp experiments using adult rat ventricular cells.…”
Section: Methodsmentioning
confidence: 99%
“…Complex interactions between ion channels are resulted in producing the cardiac AP in the so-far-defined models [ 8 , 9 , 11 , 27 ]. We wish to know the relative contributions of each voltage-gated state variable to AP termination to be able to understand the dynamics under the complex interactions.…”
Section: Methodsmentioning
confidence: 99%
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“…Conductance-based models have been used to generate the spiking activity of electrically excitable cells including heart cells, pancreatic-beta cells and neurons and it has proved itself as a very successful tool to mimic the spiking activity and analyze the systems deeply [13][14][15].…”
Section: Introductionmentioning
confidence: 99%