2021
DOI: 10.1186/s42787-021-00125-8
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Mathematical modeling of the impact of treatment on the dynamics of typhoid

Abstract: In this paper, we propose a mathematical model for the transmission of typhoid which analyzes the impact of treatment of the infected individuals on the dynamics of the disease. The model consists of human population and pathogen population. The human population is subdivided into three compartments, namely susceptible individuals, infected individuals, and recovered individuals and pathogen population comprises one compartment. We derived the basic reproduction number $${\mathcal {R}}_0$$ … Show more

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Cited by 7 publications
(5 citation statements)
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“…The mathematical model for typhoid disease was developed by considering various interventions to control the disease and reduce infection risk. The intervention used most in controlling the disease is treatment [3,18,43,47,50,53,55,57]. Based on some research, treatment is confirmed as the best intervention in controlling the spread of typhoid disease.…”
Section: Systematic Literature Review Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…The mathematical model for typhoid disease was developed by considering various interventions to control the disease and reduce infection risk. The intervention used most in controlling the disease is treatment [3,18,43,47,50,53,55,57]. Based on some research, treatment is confirmed as the best intervention in controlling the spread of typhoid disease.…”
Section: Systematic Literature Review Resultsmentioning
confidence: 99%
“…The basic compartmental mathematical models to describe the spread of disease are introduced [15][16][17]. The latest mathematical models have involved some factors in the typhoid disease spread, such as treatment in an effort on the infected population [18,19] and the existence of flies as a disease carrier vector that spreads the bacteria Salmonella on food [20]. Moreover, some researchers developed a non-autonomous mathematical model [8,21] to study typhoid transmission by considering the effect of seasonal conditions and some time-dependent parameters.…”
Section: Introductionmentioning
confidence: 99%
“…We carry out numerical simulations of the model (1), using MATLAB ode45 solver as carried out in [15]. The parameter values used are presented in Table 1, and the initial populations are taken to be S 0 = 10000, E k 0 = 2000, I k 0 = 100, P k 0 = 1600, and R 0 = 1000.…”
Section: Numerical Simulationmentioning
confidence: 99%
“…The local and global stability of equilibrium points is also studied 8 . A mathematical model for the transmission of typhoid was developed by Nyaberi and Musaili, and it examines the effects of treatment on the dynamics of the illness 9 . Birger et al studied mathematical models of typhoid transmission by considering FQNS and multidrug resistance separately.…”
Section: Introductionmentioning
confidence: 99%