Mathematical Models of the Arabidopsis Circadian Oscillator
Lucas Henao,
Saúl Ares,
Pablo Catalán
Abstract:We review the construction and evolution of mathematical models of the Arabidopsis circadian clock, structuring the discussion into two distinct historical phases of modeling strategies: extension and reduction. The extension phase explores the bottom-up assembly of regulatory networks, introducing as many components and interactions as possible to capture the oscillatory nature of the clock. The reduction phase deals with functional decomposition, distilling complex models to their essential dynamical reperto… Show more
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