Mating allocations in Nordic Red Dairy Cattle using genomic information

Bengtsson, Christian; Stålhammar, H.; Thomasen, Jørn Rind; Eriksson, Staffan; Fikse, W.F.; Strandberg, E.

doi:10.3168/jds.2021-20849

Cited by 10 publications

(5 citation statements)

References 39 publications

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“…In our work, we show, for the first time, that the risk of having a dead calf is increased in heifers and cows that are daughters of AH1-C bulls. It can be concluded that these data will undoubtedly be useful in the preparation of mating programs, and the conclusions are consistent with the those of other studies [2].…”

Section: Analysis Of Calving Results and Reproductive Qualities Of Co...supporting

confidence: 88%

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

Tulinova

Vasilyeva

Romanova

et al. 2022

SJLSA

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The aim of our study was to analyze the reproduction dynamics and fertility rates of the Ayrshire cattle population in Russia and to assess the level of influence of the AH1 haplotype on the incidence of stillbirth. For an overall fertility estimate, we used 390,769 records of 67 dairy herds in Russia from 2003 to 2018. Against the background of stable population growth, the average stillbirth rate was 3.33% and the abortion rate was 0.075%. A high percentage of stillbirth (5.13%) from heifers the first fertilization event, and there was a high rate of abortions in older cows (11 calving, 1.76%). An analysis of 62,534 records of bulls with the rs475678587C>T variant of UBE3B gene (AH1 haplotype) (n = 69, of which 51 bulls were free from and 18 were carriers of AH1) for the period 2002 to 2018 showed that the proportion of female offspring of AH1-C bulls completing at least one full period of lactation was about one-third of the total livestock. An analysis of the results of mating with AH-F and AH-C bulls for the broodstock as a whole (without taking into account the female genotype) did not reveal significant differences in the number of stillbirths and abortions. Linear regression analysis showed that the status of AH1 bulls did not significantly affect stillbirth rates. An analysis of the results of calving and the reproductive ability of the offspring of AH-C bulls showed an increase in the frequency of stillbirths, confirmed by the results of linear regression analysis, which revealed a significant effect of bull fathers carrying AH1on the proportion of stillbirths experienced by their daughters. Our studies confirm that the rs475678587C>T variant of the UBE3B gene (haplotype AH1) has a significant effect on the rate of stillbirth of a cow or heifer if their father is a carrier of this genetic defect.

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Section: Analysis Of Calving Results and Reproductive Qualities Of Co...supporting

confidence: 88%

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

Tulinova

Vasilyeva

Romanova

et al. 2022

SJLSA

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“…We chose not to include pedigree‐based inbreeding measures due to poor pedigree completeness for the oldest animals. However, Bengtsson et al (2022) estimated high correlations (≥0.83) between genomic and pedigree‐based relationship measures in Nordic RDC born 2011–2020.…”

Section: Discussionmentioning

confidence: 99%

Changes in genomic inbreeding and diversity over half a century in Swedish Red and Swedish Holstein dairy cattle

Eriksson

Strandberg

Johansson

2023

J Animal Breeding Genetics

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Swedish Red (SR) and Swedish Holstein (SH) are the dominating commercial dairy cattle breeds in Sweden. Both breeds have undergone substantial changes during the last half century due to intensive selection for breeding goal traits, but also resulting from increased international exchange of breeding animals and genetic drift. The aim of this study was to learn more about changes in genomic diversity and inbreeding in these two breeds over time. Therefore, semen samples from old bulls were genotyped using the 150K Genomic Profiler SNP array and combined with 50K SNP array genotype data, obtained for more recent bulls from the Nordic Cattle Genetic Evaluation. Different measures of level of homozygosity, genomic inbreeding, relatedness and changes in allele frequency were estimated for bulls born during different time periods from the 1950s until 2020.In total, more than 33,000 SNPs for 9737 SR and 5041 SH bulls were included in the analysis using PLINK v1.9. The results showed higher average homozygosity for SR than for SH bulls up to around 2000, but the difference was very small after that. The average inbreeding coefficients based on deviation from expected How to cite this article: Eriksson, S., Strandberg, E., & Johansson, A. M. (2023). Changes in genomic inbreeding and diversity over half a century in Swedish Red and Swedish Holstein dairy cattle.

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“…Moreover, linear programming has also been utilized to optimize mating allocation, which can directly obtain specific mating combinations. By adding genome information, feeding cost and other parameters, the LP method can help breeders achieve a multi-objective breeding program [ 36 , 37 , 38 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Linear Programming and Optimal Contribution Selection Approaches for Long-Term Selection on Beef Cattle Breeding

Zheng,

Wang,

Niu

et al. 2023

Biology

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The optimized selection method can maximize the genetic gain in offspring under the premise of controlling the inbreeding level of the population. At present, genetic gain has been largely improved by using genomic selection in multiple farm animals. However, the design of the optimal selection method and assessment of its effects during long-term selection in beef cattle breeding are yet to be fully explored. In this study, a simulated beef cattle population was constructed, and 15 generations of simulated breeding were carried out using the linear programming breeding strategy (LP) and optimal contribution selection strategy (OCS), respectively. The truncation selection strategy (TS−I and TS−II) was used as the control. During the breeding process, genetic parameters including genetic gain, average kinship coefficient, QTL effect variance, and average observed heterozygosity were calculated and compared across generations. Our results showed that the LP method can significantly improve the genetic gain in the population, especially the genetic performance of the traits with high heritability and the traits with high weight in the breeding process, but the inbreeding level of the population is higher under LP strategy. Although the genetic gain in the population under the OCS strategy is lower than the TS−II strategy, this method can effectively control the inbreeding level of the population. Our findings also suggest that the LP and OCS method can be used as an effective means to improve genetic gain, while the OCS method is a more ideal method to obtain sustainable genetic gain during long-term selection.

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Mating allocations in Nordic Red Dairy Cattle using genomic information

Cited by 10 publications

References 39 publications

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

Changes in genomic inbreeding and diversity over half a century in Swedish Red and Swedish Holstein dairy cattle

Evaluation of Linear Programming and Optimal Contribution Selection Approaches for Long-Term Selection on Beef Cattle Breeding

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