Mating Enhances Expression of Hormonal and Trophic Factors in the Midbrain of Female Rats

Abstract

Among female rats, mating enhances neurosteroid formation in the midbrain ventral tegmental area (VTA; independent of peripheral steroid-secreting glands, ovaries, and adrenals). The sources/targets for these actions are not well understood. In Experiment 1, proestrous rats engaged in a mating paradigm, or did not, and the midbrains had been assessed via the Affymetrix rat genome microarrays. In Experiment 2, the influence of gonadal and adrenal glands on the expression of these genes was assessed in rats that were proestrous, ovariectomized (OVX), or OVX and adrenalectomized (ADX). The microarrays revealed 53 target genes that were significantly up-regulated (>2.0-fold change) in response to mating. Mating significantly enhanced the midbrain mRNA expression of genes involved in hormonal and trophic actions: Gh1, S100g, and Klk1b3 in proestrous, but not OVX and/or ADX, rats; Fshb in all but OVX/ADX rats; and lutenizing hormone β and thyroid-stimulating hormone (TSH) β in all rats. Thus, mating enhances midbrain gene expression independent and dependent of peripheral glands.

Effect of cycle ergometer training using different intensities in increasing catecholamine hormone of overweight females

“…Evidence in a study of the role of hormones in sports reported that the catecholamine hormone stimulates the occurrence of lipolysis by stimulating β-adrenal receptors which occur when exercising physical activity (Frye and Chittur 2020). In connection with the above, other researchers also found that the results of aerobic exercise have an effect on fat by stimulating the hormones that play an important role in reducing fat.…”