This study presents a review of femicides over 31 years (1991–2021) from the Republic of Ireland. A total of 253 cases were located and reviewed, of those 125 were intimate partner homicides (IPH) and 128 non-intimate homicides (NIH). One hundred and ninety-nine (78%) girls and women were killed by a male known to them – intimate partner (husband, partner, boyfriend, ex-partner, ex-boyfriend) (n = 125; 48%), family members (son, grandson, brother, cousin) ( n = 25; 10%) and/or acquaintances ( n = 49; 19%) from adolescence to old age. Thirty-one (12%) were killed by a stranger and 23 cases remain unsolved at this time. The method of killing depended on the relationship and age of the victim and perpetrator. The majority of IPH victims were less than 45 years of age ( n = 101). Twenty-four were over 45 years of which six were over 60 years of age. The leading method of killing in IPHs was stabbing and strangulation and this was more prevalent in those aged between 26 and 45 years. As age increases, IPH decreases with the exception of cases of IP homicide-suicide. Adolescents (13–19 years) and young women (20–25 years) were more often killed by strangulation. Strangulation was also the leading cause of death in stranger killings particularly with sexual violence. There were 20 cases of matricide, with 17 perpetrators suffering from a mental illness at the time of the killing. The leading method of homicide in non-intimate homicides was blunt force trauma.