In cognitive radio networks (CRNs), establishing a communication link between a pair of secondary users (SUs) requires them to rendezvous on a common channel which is not occupied by primary users (PUs). Under time-varying PU traffic, asynchronous sequence-based channel hopping (CH) with the maximal rendezvous diversity is a representative technique to guarantee an upper bounded time-torendezvous (TTR) for delay-sensitive services in CRNs, without requiring global clock synchronization.Maximum TTR (MTTR) and maximum conditional TTR (MCTTR) are two commonly considered metrics for evaluating such CH sequences, and minimizing these two metrics is the primary goal in the sequence design of various paper reported in the literature. In this paper, to investigate the fundamental limits of these two metrics, we first derive lower bounds on the MCTTR and MTTR, and then propose an asymmetric design which has the minimum MCTTR and an improvement on MTTR than other previously known algorithms. Moreover, when the number of licensed channels is odd, our proposed design achieves the minimum MTTR. We also present the TTR performance of the proposed design via simulation. DRAFT This paper continues the work to investigate asynchronous CH sequences with the maximal rendezvous diversity under this objective. The follow-on tasks after initial rendezvous, such as channel contention procedure and data packet transmission, are outside the scope of this paper.Obviously, MTTR and MCTTR provide upper bounds on the TTR for two extreme channel conditions, and hence have been commonly considered for those applications that have stringent worst-case TTR requirement. DRAFT