2023
DOI: 10.3390/biomedicines11112953
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Matrix Metalloproteinase 9/microRNA-145 Ratio: Bridging Genomic and Immunological Variabilities in Thyroid Cancer

Eman A. Toraih,
Mohamed H. Hussein,
Essam Al Ageeli
et al.

Abstract: Matrix metalloproteinase 9 (MMP9) and microRNA-145 (miR-145) have emerged as essential biomarkers in thyroid cancer progression and metastasis. However, their combined evaluation and clinical utility as a unified prognostic marker across diverse thyroid cancer subgroups remain unexplored. We investigated the diagnostic and prognostic value of the MMP9/miR-145 ratio in thyroid cancer, hypothesizing it may overcome inter-patient heterogeneity and serve as a versatile biomarker regardless of genetic mutations or … Show more

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“…This work features the requirement for an exhaustive comprehension of both genomic and immunological elements in disentangling the intricacies of disease pathology. Wu et al [ 19] investigate the capability of peeled kidney cells from pee for the early determination and guess of Persistent Kidney Sickness (CKD). The review acquaints a clever methodology with painless diagnostics, underlining the significance of investigating elective hotspots for biomarkers.…”
Section: Related Workmentioning
confidence: 99%
“…This work features the requirement for an exhaustive comprehension of both genomic and immunological elements in disentangling the intricacies of disease pathology. Wu et al [ 19] investigate the capability of peeled kidney cells from pee for the early determination and guess of Persistent Kidney Sickness (CKD). The review acquaints a clever methodology with painless diagnostics, underlining the significance of investigating elective hotspots for biomarkers.…”
Section: Related Workmentioning
confidence: 99%