Mature and Immature Solid Teratomas Involving Uterine Corpus, Cervix, and Ovary

Abstract

Extragonadal teratomas are rare, and localization in the endometrium and cervix is exceptional, with only up to 10 case reports documented so far in the English literature. We present here the case of a 46-year-old patient who presented with simultaneous immature teratoma in the endometrium and mature teratomas in the ovary in association with gliomatosis peritonei but with no evidence of gestational origin; she subsequently developed multiple solid mature teratomas in the cervix and parauterine tissue. No other similar cases have been previously reported to our knowledge. There are many similarities between the patient’s pattern of recurrence and “growing teratoma syndrome (GTS).” Although the patient was not treated with chemotherapy after her first presentation and this case does not meet formal criteria for GTS, we believe that the pattern and histology of recurrences in this case represent a variant of GTS. Considering that the initial presentation in this case was endometrial and ovarian makes the occurrence of GTS-like syndrome even more unique.

Collision Glial Neoplasms Arising in an Ovarian Mature Cystic Teratoma: A Rare Event

“…A careful gross examination is considered very important when handling specimens of ovarian teratomas with solid areas. Extensive tissue sampling of any solid areas would likely divulge morphologic features of a significant diagnostic and prognostic value, especially immature elements [16]. Therefore, we cannot emphasize enough the importance of good tissue sampling to exclude grade 1 immature teratoma.…”

Mature cystic teratoma of the uterus presenting as an endometrial polyp in a patient with a history of ovarian mature cystic teratoma with gliomatosis peritonei and ovarian endometriosis: a case report

“…Teratomas of the uterus are rare neoplasms. To date, mature or immature teratomas of the uterus have been reported in 10 cases [3][4][5][6][7][8][9][10][11][12]. Most reported cases were mature teratomas; however, there are two reports of immature teratomas [8,12] and one report of an immature teratoma coexisting with adenocarcinoma [6].…”

Immature teratoma arising from uterine corpus in an 11‐year‐old girl: Case report and review of the literature

“…Teratomas usually arise in the gonads, while extragonadal teratomas are very rare and account for 2–5% of germ cell tumors 3 . Primary teratomas of the uterus have rarely been reported since 1929 4–7 . Here, the case of an 11‐year‐old patient who had an immature teratoma in her uterus and a mature teratoma in her ovary is presented.…”

“…3 Primary teratomas of the uterus have rarely been reported since 1929. [4][5][6][7] Here, the case of an 11-yearold patient who had an immature teratoma in her uterus and a mature teratoma in her ovary is presented.…”